Knowledge · Natural Substances

Humic Acid Complexes

Humic acid complexes are formed during the slow decomposition of plants, primarily from lignin; human studies show improvements mainly for shilajit and peat applications.

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We evaluated 71 human studies on Humic acid complexes, including 19 randomised controlled trials and 3 meta-analyses or systematic reviews; the controlled studies include 1,611 participants in total. As of 3 October 2026.

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1. What Is Humic Acid Complexes? Occurrence, Origin and Forms

Humic acid complexes are mixtures of large organic molecules that form when dead plant matter is broken down and transformed over long periods – above all lignin, the woody substance of plants. There is no single, uniform humic acid: origin, degree of maturation and extraction determine which molecules a preparation contains. They are divided into humic acids, fulvic acids and humins.

Humic acid complexes occur in soils, in peat and bog, in brown coal and leonardite, in compost and in rivers, lakes and their sediments. Shilajit, also called mumijo, is a resin-like substance that seeps from rock in high mountain ranges such as the Himalayas and the Altai and consists largely of humic substances.

Preparations taken by mouth are mostly obtained from leonardite, brown coal or peat: the humic substances are dissolved with alkali, separated and purified. Shilajit is purified and dried. There is also fulvic acid manufactured from carbohydrates (carbohydrate-derived fulvic acid, CHD-FA). Baths and packs use medicinal peat.

Forms and Preparations Studied

  • Humic acids and humates, such as sodium or potassium humate
  • Fulvic acid, including carbohydrate-derived fulvic acid (CHD-FA)
  • Shilajit (mumijo, momiai, asphaltum, mineral pitch)
  • Drinkable peat and peat extracts taken by mouth
  • Peat baths, peat packs and peloids made from peat
  • Combination products containing humic acid complexes – the other ingredients are named in each case

Not covered on this page:

  • Sulphur, brine, radon and mineral baths without peat, and mineral mud (fango) without peat → Balneotherapy and Moor Therapy
  • Humus as a soil parameter in agricultural and environmental studies
  • Isolated lignin from the wood and paper industry

2. What Does Humic Acid Complexes Do? Results by Area

AreaResult in controlled studiesStrength of evidenceStudiesParticipants
Bones, joints and musclesmostly improvedhigh1 meta-analyses · 11 controlled · 14 other584
Hormones and fertilitymostly improvedhigh1 meta-analyses · 4 controlled · 3 other232
Energy, performance and fatiguemostly improvedhigh0 meta-analyses · 5 controlled · 6 other415
Inflammation and immune systemmixedmoderate0 meta-analyses · 5 controlled · 12 other567
Metabolism and blood sugarmostly improvedmoderate0 meta-analyses · 3 controlled · 7 other292
Skin and woundsmostly improvedmoderate0 meta-analyses · 3 controlled · 4 other66
Digestion and gutmostly no differenceunclear0 meta-analyses · 1 controlled · 6 other0
Brain and cognitionobservational data onlyunclear0 meta-analyses · 0 controlled · 4 other0
Other outcomesmostly improvedhigh0 meta-analyses · 12 controlled · 23 other1,055

How to read the table: counted are human studies whose results concern the area. “High” means at least one meta-analysis and two controlled studies showing improvement, or at least three controlled studies of which three quarters show improvement, with at least 300 participants in total. “Moderate” means at least two controlled studies showing improvement, as a majority, or one meta-analysis alongside controlled studies. “Low” means one controlled study showing improvement. Where an area has no controlled study, the strength of evidence is at most “low” (result “reviews only” or “observational data only”). Everything else is “unclear”. A study counts as showing improvement when at least half of its outcomes in this area improved. Reviews of combination products do not count as meta-analyses; results that only describe side effects or shares of users do not count as an effect. The same study is counted only once.

3. What the Studies Show in Detail

Humic Acid Complexes, Bones, Joints and Muscles: Human Studies

For bones, joints and muscles, peat applications relieved pain in controlled studies: in knee osteoarthritis under peat packs compared with a mere hot pack 19 and under peat compresses compared with a sham treatment 26, in back pain under peat pack plus trunk training compared with training alone 20. In another study on back pain, pain and mobility improved under peat therapy as well as under ultrasound and magnetic therapy; for pain, ultrasound performed best 27. A meta-analysis on mud therapy, which included peat in addition to clay and mineral mud, found less pain and better physical function 1. Under shilajit, muscle strength increased in randomized studies 6 and fatigue-related loss of strength decreased 21; after a tibial fracture, the bone healed faster under mumijo (Momiai) 5. Oral potassium humate relieved pain in knee osteoarthritis in a small randomized study 14. The strength of evidence is high, but many studies are small, and the comparison conditions as well as the composition of the preparations differ considerably.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
1 Balakrishna et al. 2026meta-analysis · 2,651 participantsPelotherapy (mud, peat, clay, mineral-rich mud); Follow-up up to 6 months; vs. Sham, usual care, or no treatmentPain post-intervention: improved (SMD -0.74; 95% CI -0.91 to -0.57); Pain at 3 months: improved (SMD -0.61; 95% CI -0.81 to -0.41); Pain at 6 months: improved (SMD -0.49; 95% CI -0.71 to -0.27)
2 Richard et al. 2025systematic reviewBalneotherapy: healing waters, peloids, peat packs, sepiolite clay; vs. heterogeneous controls, no meta-analysis possiblePain: improved
5 Seyed et al. 2020randomised controlled · 160 participantsMomiai (shilajit) capsules; two 500 mg capsules daily; 28 days; vs. Placebomean time to tibial bone union: improved (129 days in the experimental group, while it was 153 days in the placebo group (p < 0.049))
6 Divya et al. 2026randomised controlled · 100 participantsTruBlk™ Shilajit resin (≥60% fulvic acid, ≥10% shilarathenes™); 250 mg twice daily; 90 days; vs. Placebo, double-blind, randomised, multicentre1RM leg press: improved (+26.0% vs +18.4%; p=0.0003, d=0.74); muscle endurance: improved (+110.8% vs +80.5%; p=0.0017, d=0.60); delayed onset muscle soreness (DOMS): improved (p=0.036)
8 Darshani et al. 2025randomised controlled · 66 participantsShilAbsorb™ gummies (Shilajit plus herbs); two gummies daily; 60 days; vs. PlaceboSkeletal muscle mass: improved (4.47% more than placebo); Leg press 1RM: improved (p<0.001); Chest press 1RM: improved (p<0.001)
14 C.E.J. et al. 2010randomised controlled · 28 participantsPotassium humate (from brown coal) vs. lactose; 600 mg three times daily; 6 weeks per phase, 14 weeks total; vs. Placebo (lactose), randomized double-blind crossoverWOMAC pain subscale: improved; WOMAC total and subscale scores: improved
16 Neltner et al. 2024randomised controlledOral Shilajit supplementation; 500 mg/day or 1000 mg/day; 8 weeks; vs. PlaceboSerum pro-c1α1 (type 1 collagen synthesis): improved (Low dose: p = 0.008, d = 1.2; High dose: p = 0.007, d = 1.3); Proportion exceeding minimal clinically important difference: improved (p = 0.03)
19 Myeongkyu et al. 2020randomised controlledPeat pack applied to both knees; 20 minutes per session, 8 sessions over 5 days; 5 days; vs. Hot-pack-only controlPain (VAS): improved (p < 0.001); Serum COMP: no difference; Gait velocity: improved (p = 0.002)

Further studies in this area: 20 21 25 26 27 33 34 36 39 41 49 50 53 54 55 56 62 68

Humic Acid Complexes, Hormones and Fertility: Human Studies

In men, testosterone increased under shilajit in three randomized studies 6722; a systematic review classifies shilajit as possibly effective in men with late-onset hypogonadism 3. One study also found a better sexual response 7, another an increase in DHEAS with unchanged levels of LH and FSH 22. A mixed preparation of shilajit with ashwagandha, ginger, black pepper, Mucuna pruriens and akarkara also improved free and total testosterone in a randomized controlled study 8. The strength of evidence is high, but the studies tested almost exclusively shilajit in men; for peat bath, drinkable peat and other humic acid complexes as well as for women, hardly any robust data are available.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
3 Morgado et al. 2024systematic review27 testosterone boosters, including purified Shilajit extract (PrimaVie™); vs. PlaceboSerum total testosterone: improved (possibly effective)
6 Divya et al. 2026randomised controlled · 100 participantsTruBlk™ Shilajit resin (≥60% fulvic acid, ≥10% shilarathenes™); 250 mg twice daily; 90 days; vs. Placebo, double-blind, randomised, multicentrefree testosterone: improved (+21.8% vs −2.9%; p=0.030, d=0.45); total testosterone: improved (+15.6% vs −3.8%; p=0.038, d=0.43)
7 Darshani et al. 2025randomised controlled · 66 participantsShilAbsorb™ gummies (Shilajit); 90 days; vs. placebototal testosterone: improved (25.39% increase); free testosterone: improved (9.51% increase); sexual response (orgasm scores): improved (17.59% greater improvement)
8 Darshani et al. 2025randomised controlled · 66 participantsShilAbsorb™ gummies (Shilajit plus herbs); two gummies daily; 60 days; vs. PlaceboFree testosterone: improved (10.33%); Total testosterone: improved (9.34%); Cortisol: improved (26.5%)
22 S et al. 2015randomised controlledPurified Shilajit (Ayurvedic rasayana); 250 mg twice a day; 90 consecutive days; vs. Placebo, randomised, double-blindTotal testosterone: improved (P < 0.05); Free testosterone: improved (P < 0.05); DHEAS: improved (P < 0.05)
40 Tuhin et al. 2010study · 35 participantsProcessed Shilajit (PS), capsule; 100 mg twice daily after major meals; 90 days; vs. Before-after comparison, no control groupTotal sperm count: improved (+61.4%); Spermia: improved (+37.6%); Motility: improved (12.4-17.4% after different time intervals)
66 R. et al. 2020reviewShilajit with Triphala Kwathmanagement of hypothyroidism: unclear
68 Beer et al. 2013reviewTherapeutic peat (peloid)Therapeutic use of peat for fertility treatment: unclear

Humic Acid Complexes, Energy, Performance and Fatigue: Human Studies

In two randomized studies in men, shilajit improved muscular endurance and lowered perceived exertion 6; in the other, maximal oxygen uptake increased, and fatigue decreased somewhat more than under placebo 7. A mixed preparation of shilajit and herbs improved endurance in strength exercises 8. The strength of evidence is high, but the controlled studies predominantly tested shilajit alone or in mixtures, mostly included healthy, trained men and were partly small; for humic acids, fulvic acid, drinkable peat or medicinal peat as a single preparation for fatigue, controlled data are lacking.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
4 Victoria et al. 2025randomised controlled · 166 participantsPlacebo, PE 500 mg, PE 1000 mg, chromium 400 µg with 6 mg PE and 6 mg shilajit, chromium 800 µg with 12 mg PE and 12 mg shilajit; shilajit 6 mg/day (Cr-400) or 12 mg/day (Cr-800), once daily; 12 weeks; vs. placebo, parallel, double-blind, randomizedbody composition, strength, and aerobic capacity: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10)
6 Divya et al. 2026randomised controlled · 100 participantsTruBlk™ Shilajit resin (≥60% fulvic acid, ≥10% shilarathenes™); 250 mg twice daily; 90 days; vs. Placebo, double-blind, randomised, multicentrerating of perceived exertion (RPE): improved (p=0.002); VO₂max: improved (+3.8% vs +2.9%; p=0.032, d=0.41)
7 Darshani et al. 2025randomised controlled · 66 participantsShilAbsorb™ gummies (Shilajit); 90 days; vs. placeboVO2 max: improved (5.92%); Fatigue Severity Scale: improved (4.14% greater reductions)
8 Darshani et al. 2025randomised controlled · 66 participantsShilAbsorb™ gummies (Shilajit plus herbs); two gummies daily; 60 days; vs. PlaceboEndurance (repetitions at 50% 1RM), chest: improved (7.65%); Endurance (repetitions at 50% 1RM), leg: improved (3.17%); Perceived exertion (RPE): improved
15 Gonzalez et al. 2020randomised controlled · 17 participantsmulti-ingredient preworkout supplement with ancient peat and apple extracts; single dose, one hour before sprint protocol; vs. placebo, randomized, double-blind, counterbalancedaverage power across repeated sprints: improved (PAVG (75-229 W)); peak power across repeated sprints: improved (PPK (79-209 W)); average velocity across repeated sprints: no difference (2.34-5.87 m·s, p ≤ 0.002)
37 Stier-Jarmer et al. 2017study · 78 participantsmoor bath (moor application); 42 °C, 20 min, followed by 20 min rest; 7 applications over 3 weeks; vs. pre-post comparison without control groupsalivary cortisol: improved (Z = -3.355, p = 0.0008); salivary cortisol in week 3: no difference (non-significant decrease)
41 Divya et al. 2026study · 25 participantsTruBlk™ Shilajit Resin; 500 mg/day (250 mg twice daily); 28 days; vs. no control group (open-label single-arm)Fatigue Severity Scale: improved (decreased by 32.40% (p < 0.001)); rating of perceived exertion: improved (decreased by 23.63% (p < 0.001)); maximal oxygen uptake (VO₂ max): improved (+1.36%, p < 0.001)
55 Dr. et al. 2025reviewstandardized Shilajit extracts (Asphaltum punjabianum); 250-500 mg/day; vs. no uniform comparator; review of preclinical and clinical studiesfatigue resistance: improved

Further studies in this area: 57 63 69

Humic Acid Complexes, Inflammation and Immune System: Human Studies

In hay fever and atopy, skin test reactions weakened in two small randomized studies, with fulvic acid (CHD-FA) 13 and with oral potassium humate 11; in the potassium humate study, the eosinophil count also decreased, while immune cell functions such as neutrophil adhesion and basophil stimulation remained unchanged 11. The strength of evidence is moderate: the controlled studies are small, some without a placebo group, and the larger investigations concern combination preparations or other diseases. Oral humates and fulvic acid, peat applications, and mixtures were studied; for peat baths, drinkable peat, and shilajit as a single preparation, predominantly uncontrolled observations are available, and a case report describes an exercise-induced anaphylaxis in which shilajit was considered a co-trigger 44.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
11 Justin et al. 2008randomised controlled · 40 participantsoral potassium humate; vs. random assignment, no placebo group reportedskin prick test: improved (significant decrease); eosinophil counts: improved (significant decrease); neutrophil adhesion: no difference (No significant differences)
13 Justin et al. 2012randomised controlled · 30 participantscarbohydrate-derived fulvic acid (CHD-FA), 3.8%; 5–40 mL escalating; 20 or 40 mL twice daily; 3 days or 1 week each, with washout; vs. placebo, double-blind, crossoverskin prick test response: improved (significant decrease)
14 C.E.J. et al. 2010randomised controlled · 28 participantsPotassium humate (from brown coal) vs. lactose; 600 mg three times daily; 6 weeks per phase, 14 weeks total; vs. Placebo (lactose), randomized double-blind crossoverhs-CRP: improved
23 M. et al. 2018controlled · 332 participantsCHD-FA in wellness drink F0210; vs. placebo, double-blind, paralleltime to ART indication (event): no difference (p = 0.5724); CD4 count: unclear; HIV-1 viral load: unclear
24 Strelis et al. 1991controlled · 137 participantsPeloidin phonophoresis, humisol injections, torfotum injections; vs. Control group without mud preparationscellular immunity indices: improved; immunoglobulins G: improved
40 Tuhin et al. 2010study · 35 participantsProcessed Shilajit (PS), capsule; 100 mg twice daily after major meals; 90 days; vs. Before-after comparison, no control groupPus and epithelial cell count: improved
41 Divya et al. 2026study · 25 participantsTruBlk™ Shilajit Resin; 500 mg/day (250 mg twice daily); 28 days; vs. no control group (open-label single-arm)C-reactive protein (CRP): improved (declined by 25.35% (p = 0.023))
42 N. et al. 2026case series · 20 participantsfulvic acid-based gel; 21 days topical application, assessment until day 28Inflammation area by autofluorescence stomatoscopy: improved (significant reduction)

Further studies in this area: 44 46 47 49 51 57 60 62 64

Humic Acid Complexes, Metabolism and Blood Sugar: Human Studies

A randomized study with shilajit gummies found no difference in body weight, BMI, and waist circumference 7. A study with a mixture of shilajit and agnimantha showed a lower body mass (BMI) and lower total cholesterol compared with another herbal preparation 9. The strength of evidence is moderate; it remains open whether the effects are due solely to the humic acid complexes and whether they can be confirmed in healthy people.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
4 Victoria et al. 2025randomised controlled · 166 participantsPlacebo, PE 500 mg, PE 1000 mg, chromium 400 µg with 6 mg PE and 6 mg shilajit, chromium 800 µg with 12 mg PE and 12 mg shilajit; shilajit 6 mg/day (Cr-400) or 12 mg/day (Cr-800), once daily; 12 weeks; vs. placebo, parallel, double-blind, randomizedinsulin sensitivity: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10); blood lipid profiles: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10)
7 Darshani et al. 2025randomised controlled · 66 participantsShilAbsorb™ gummies (Shilajit); 90 days; vs. placebobody weight, BMI, waist circumference: no difference
9 Eranga et al. 2026randomised controlled · 60 participantsAgnimantha Shilajit Yoga (AS) vs. Bilvadi Yoga (BY); AS 0.5 g twice daily; BY 5 g twice daily with 10 mL honey; vs. AS vs. BY (Bilvadi Yoga)Body mass index: improved (Decreased from 3.60 to 2.00 (p < 0.001)); Total cholesterol: improved (reduced from 244.68 to 189.04)
43 Singh et al. 2025case report · 1 participantsShilajatu Darvi Yoga: Shilajit plus Berberis aristata decoction; 5 mL twice daily with warm water, empty stomach; 3 monthsHbA1c: improved (12.8 to 7.3); fasting blood sugar: improved (224 to 122); postprandial blood sugar: improved (437 to 149)
48 Sharma et al. 2003studyShilajit; 2 g daily; 45 daysserum triglycerides: improved; serum cholesterol: improved; HDL cholesterol: improved
49 Н. et al. 2000studySodium humate balneotherapy; low concentration of the preparationlipid modulating effect: improved; metabolic processes: improved
52 Sakshi et al. 2026reviewArogyavardhini Vati, Ayurvedic herbo-mineral formulation containing ShilajitLipid metabolism: improved
54 Ashif et al. 2025reviewShilajit (Asphaltum Punjabianum), purified; well tolerated even at very high doses; several weeks of continuous intake; vs. no comparison; myths checked against evidencemetabolic processes: improved

Further studies in this area: 57 58

Humic Acid Complexes, Skin and Wounds: Human Studies

In eczema, the investigators assessed the response with fulvic acid (CHD-FA) for topical application as better than with a plain care cream in a small randomized study; however, severity and redness improved in both groups 12. A controlled, non-randomized study with oral shilajit found better skin blood flow and altered activity of genes for connective tissue and vessels in middle-aged women 30. The strength of evidence is moderate; the studies are small, and the shilajit study is not randomized. It remains open whether the findings apply to other preparations and over longer periods.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
12 Justin et al. 2011randomised controlled · 36 participantstopical CHD-FA versus placebo (emollient); twice daily; four weeks; vs. placebo/emollient therapyeczema severity: improved; erythema: improved; scaling: improved
29 Rondanelli et al. 2012controlled · 30 participantsAssociation of Massaciuccoli peat and sodium chloride water of Undulna Thermae; 2 weeks; vs. Intervention group versus control (not further described)skin elasticity: improved (+5.52%, p < 0.001); subcutaneous perfusion: improved
30 Amitava et al. 2019controlledoral shilajit supplement; 125 or 250 mg bid; 14 weeks; vs. placebo and baselineskin perfusion: improved; expression of ECM and vascular genes: improved
42 N. et al. 2026case series · 20 participantsfulvic acid-based gel; 21 days topical application, assessment until day 28Complete epithelialization of erosions: improved (92% of patients by day 28)
56 Aleksander et al. 2025reviewpeat and sapropel peloids containing humic, fulvic, hymatomelanic acids; vs. classical thermal versus non-thermal pelotherapy techniqueseffectiveness in skin disorders: improved
62 Tian et al. 2022reviewMud (raw and refined clay)Glutathione enzyme and superoxide dismutase activity in skin: improved; Skin microbial community: improved; Skin drug delivery: improved
67 Varsha et al. 2019reviewFulvic acid as topical cream/lotion in a moisturizing base; vs. Emollients aloneEffectiveness in skin inflammation: improved; Tolerance

Humic Acid Complexes, Digestion and Gut: Human Studies

For digestion and the gut, two controlled studies are available. In people with diarrhea-predominant irritable bowel syndrome, a randomized study found no confirmed difference from placebo with humic acids 18. Women responded better than men 18. A wellness drink with fulvic acid (CHD-FA) was overall well tolerated in a controlled study of 332 HIV-positive people 23. However, gastrointestinal complaints occurred more frequently with it than with placebo 23. The strength of evidence is overall unclear, as the controlled findings do not give a consistent picture. Reliable statements about digestive complaints cannot be derived from this.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
18 Ingolf et al. 2021randomised controlledHumic acids versus placebo; vs. Placebo, double-blind, randomisedIBS symptom severity (IBS-SSS), main effect of treatment: no difference (F=1.56, p=0.221); Response rate (≥50-point improvement on IBS-SSS): no difference (57.9% vs. 36.8%, p=0.194); Response rate women vs. men on humic acids: improved (71.4% vs. 20.0%, p=0.045)
23 M. et al. 2018controlled · 332 participantsCHD-FA in wellness drink F0210; vs. placebo, double-blind, parallelgastrointestinal intolerance
45 Shkliaev et al. 2011case seriesSMC electrophoresis combined with peloidotherapy (Uva peat muds)proliferative activity of duodenal epithelium: improved
52 Sakshi et al. 2026reviewArogyavardhini Vati, Ayurvedic herbo-mineral formulation containing ShilajitLiver function: improved
56 Aleksander et al. 2025reviewpeat and sapropel peloids containing humic, fulvic, hymatomelanic acids; vs. classical thermal versus non-thermal pelotherapy techniqueseffectiveness in digestive system diseases: improved
61 Paul et al. 2023reviewIngredients containing fulvic acids and/or humic acids; Long-term useAdverse events from fulvic/humic acid ingredients
62 Tian et al. 2022reviewMud (raw and refined clay)Gastrointestinal tract protection and treatment of gastrointestinal diseases: improved

Humic Acid Complexes, Brain and Cognition: Human Studies

For the brain and mental performance, only observations without a control group are available for humic acid complexes. A study without a comparison group reports a better mood after rhythmic rubbing with Solum oil, a peat extract with lavender oil 35. Another study reports a better mood after a peat bath 37. Two review articles suggest benefits for mental performance from shilajit 54 and in neurodegenerative diseases from fulvic acid 64. Since no controlled studies and no meta-analyses are available, the strength of evidence is unclear; a peat extract-lavender oil mixture, a peat bath, shilajit, and fulvic acid were studied.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
35 Thomas et al. 2008study · 100 participantsSolum Oil: aqueous peat extract (1:5) 1.96 g and lavender oil 0.5 g per 10 g; 3 treatments within 24 days; 24 days; vs. no control group, pre-post comparisonMood (Bf-S): improved (25.8 (95% CI; 22.8-28.1) to 13.3 (95% CI; 11.7-15.0))
37 Stier-Jarmer et al. 2017study · 78 participantsmoor bath (moor application); 42 °C, 20 min, followed by 20 min rest; 7 applications over 3 weeks; vs. pre-post comparison without control groupmood state (Multidimensional Mood State Questionnaire): improved (improved significantly)
54 Ashif et al. 2025reviewShilajit (Asphaltum Punjabianum), purified; well tolerated even at very high doses; several weeks of continuous intake; vs. no comparison; myths checked against evidencecognitive enhancement: improved
64 Didiek et al. 2021reviewFulvic acid (FA), extracted from lignite, peat, bog and compostcombating neurodegenerative disorders: improved (highly promising results)

Humic Acid Complexes: Further Outcomes in Studies

After disc surgery, everyday resilience (Oswestry index) improved with peat mud applications 25, and in knee osteoarthritis, general health status improved with peat compresses 26. With shilajit, perceived stress 7 and signs of oxidative stress 10 decreased, and with mumijo, a lowered platelet count was less common 28. A randomized study with shilajit also showed lower muscle damage values (creatine kinase, lactate dehydrogenase) 6; with potassium humate, the liver value GGT temporarily rose in four participants, and with placebo in two 14. A meta-analysis on mud therapy, which also included peat, found no increase in serious adverse events 1. The strength of evidence is overall high, as several controlled studies are available; shilajit, mumijo, fulvic acid (CHD-FA), potassium humate, and peat applications were tested, some in combination preparations. The transferability to other humic acid complexes and the confirmation of the safety findings in larger, longer-term studies remain open.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
1 Balakrishna et al. 2026meta-analysis · 2,651 participantsPelotherapy (mud, peat, clay, mineral-rich mud); Follow-up up to 6 months; vs. Sham, usual care, or no treatmentSerious adverse events (RR 0.98; 95% CI 0.61-1.58)
2 Richard et al. 2025systematic reviewBalneotherapy: healing waters, peloids, peat packs, sepiolite clay; vs. heterogeneous controls, no meta-analysis possibleHealth-related quality of life: improved
4 Victoria et al. 2025randomised controlled · 166 participantsPlacebo, PE 500 mg, PE 1000 mg, chromium 400 µg with 6 mg PE and 6 mg shilajit, chromium 800 µg with 12 mg PE and 12 mg shilajit; shilajit 6 mg/day (Cr-400) or 12 mg/day (Cr-800), once daily; 12 weeks; vs. placebo, parallel, double-blind, randomizedpulse wave velocity: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10); flow-mediated dilation: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10); platelet aggregation: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10)
6 Divya et al. 2026randomised controlled · 100 participantsTruBlk™ Shilajit resin (≥60% fulvic acid, ≥10% shilarathenes™); 250 mg twice daily; 90 days; vs. Placebo, double-blind, randomised, multicentrecreatine kinase: improved (−33.6% vs −6.9%; p=0.030, δ=−0.26); lactate dehydrogenase: improved (−17.8% vs −4.2%; p=0.039, δ=−0.24)
7 Darshani et al. 2025randomised controlled · 66 participantsShilAbsorb™ gummies (Shilajit); 90 days; vs. placeboPerceived Stress Scale-10: improved (3.62% greater reductions)
9 Eranga et al. 2026randomised controlled · 60 participantsAgnimantha Shilajit Yoga (AS) vs. Bilvadi Yoga (BY); AS 0.5 g twice daily; BY 5 g twice daily with 10 mL honey; vs. AS vs. BY (Bilvadi Yoga)Subjective symptoms (pendulous body movements, heaviness, perspiration, thirst, hunger): improved (p < 0.001); Liver enzymes (AST, ALT, ALP): improved (p < 0.001); Creatinine: improved (p < 0.001)
10 Satish et al. 2023randomised controlled · 60 participantsPurified shilajit (Asphaltum punjabianum); 500 mg twice daily; 30 days; vs. Shilajit plus antihypertensives vs antihypertensives aloneMalondialdehyde: improved (P < 0.001); Oxidised low-density lipoproteins: improved (P = 0.015); Total antioxidant capacity: improved (P = 0.002)
13 Justin et al. 2012randomised controlled · 30 participantscarbohydrate-derived fulvic acid (CHD-FA), 3.8%; 5–40 mL escalating; 20 or 40 mL twice daily; 3 days or 1 week each, with washout; vs. placebo, double-blind, crossoversafety parameters (ECG, laboratory, examination) (remained constant throughout the trial)

Further studies in this area: 14 17 23 25 26 28 29 31 32 34 35 38 40 41 42 43 46 48 51 54 56 57 59 63 64 65 66

4. How Is Humic Acid Complexes Dosed? Preparation, Dose and Duration in Studies

The studies investigated mainly shilajit as capsules, gummies or resin, peat applications as baths, packs and peloids, as well as oral humates and fulvic acid. Some preparations were mixtures, such as shilajit with herbs or fulvic acid in a wellness drink. The doses and application durations are shown in the table.

Preparation or formDoseDurationStudy
Placebo, PE 500 mg, PE 1000 mg, chromium 400 µg with 6 mg PE and 6 mg shilajit, chromium 800 µg with 12 mg PE and 12 mg shilajitshilajit 6 mg/day (Cr-400) or 12 mg/day (Cr-800), once daily12 weeks4
Momiai (shilajit) capsulestwo 500 mg capsules daily28 days5
TruBlk™ Shilajit resin (≥60% fulvic acid, ≥10% shilarathenes™)250 mg twice daily90 days6
ShilAbsorb™ gummies (Shilajit)—90 days7
ShilAbsorb™ gummies (Shilajit plus herbs)two gummies daily60 days8
Agnimantha Shilajit Yoga (AS) vs. Bilvadi Yoga (BY)AS 0.5 g twice daily; BY 5 g twice daily with 10 mL honey—9
Purified shilajit (Asphaltum punjabianum)500 mg twice daily30 days10
topical CHD-FA versus placebo (emollient)twice dailyfour weeks12
carbohydrate-derived fulvic acid (CHD-FA), 3.8%5–40 mL escalating; 20 or 40 mL twice daily3 days or 1 week each, with washout13
Potassium humate (from brown coal) vs. lactose600 mg three times daily6 weeks per phase, 14 weeks total14
multi-ingredient preworkout supplement with ancient peat and apple extracts—single dose, one hour before sprint protocol15
Oral Shilajit supplementation500 mg/day or 1000 mg/day8 weeks16
Aviron Rapid, dietary supplement containing andrographolide, spirulina and humic acid—5 days (adolescents) and 7 days (children)17
Peat pack applied to both knees20 minutes per session, 8 sessions over 5 days5 days19
Mud pack plus core exerciseMud pack 30 min, core exercise 50 min, twice daily4 days, 8 sessions20

5. Is Humic Acid Complexes Safe? Side Effects in Studies

The studies predominantly report good tolerability. More frequently mentioned were temporary skin redness and fatigue under mud and peat applications, briefly lasting burning under topical fulvic acid, as well as gastrointestinal complaints under a fulvic acid-containing drink. One case report describes an exercise-induced anaphylaxis in which shilajit was considered a co-trigger, and in one study the liver value GGT temporarily increased under potassium humate in four and under placebo in two participants.

StudyReported side effects
1 Balakrishna et al. 2026Skin erythema 6.5%, transient fatigue 4.8%; no increase in serious adverse events
5 Seyed et al. 2020no significant difference between groups (p = 0.839)
6 Divya et al. 2026No adverse events recorded in the active group
7 Darshani et al. 2025no adverse events reported
8 Darshani et al. 2025Safety assessed, no details in abstract
11 Justin et al. 2008safety assessed via blood and nasal samples
12 Justin et al. 2011short-lived burning sensation on application, otherwise no difference
13 Justin et al. 2012no severe adverse events; safety parameters constant
14 C.E.J. et al. 2010GGT increase (4 vs. 2), normalized after discontinuation; tolerability good
17 Rada et al. 2023Low number of adverse events, no major differences between groups
18 Ingolf et al. 2021No adverse events reported; no patient discontinued
23 M. et al. 2018gastrointestinal intolerance (diarrhoea, nausea, vomiting) more frequent than placebo

6. What Remains Open: Limits of the Evidence

  • Many studies are small and of short duration.
  • The comparison conditions and the composition of the preparations differ considerably.
  • For peat bath, drinkable peat and other humic acid complexes as a single preparation for fatigue, controlled data are lacking.
  • Almost all studies on hormones and fertility tested shilajit in men; for women, hardly any robust data are available.
  • It remains open whether the effects are due solely to the humic acid complexes or to other components of mixed preparations.

7. Bottom Line: What Is Established About Humic Acid Complexes

Humic acid complexes are not a uniform substance but mixtures of large organic molecules from decomposed plant material, primarily from lignin. Human studies show improvements for shilajit and peat applications in pain, physical function, muscle strength, testosterone, endurance performance and some skin and immune parameters. The strength of evidence is high for bones, joints and muscles, hormones as well as energy and performance, moderate for metabolism, skin and immune system, and unclear for digestion as well as brain. Many studies are small, the preparations differ greatly, and controlled data are lacking for several preparations.

Frequently Asked Questions

How well has Humic acid complexes been studied in humans?

We evaluated 71 human studies on Humic acid complexes, including 19 randomised controlled trials and 3 meta-analyses or systematic reviews; the controlled studies include 1,611 participants in total. As of 3 October 2026.

Does Humic acid complexes help with bones, joints and muscles? What the studies show

We evaluated one meta-analysis or systematic review, 11 controlled studies and 14 further studies; the controlled studies include 584 participants in total. Result of the controlled studies: mostly improved. Strength of evidence under our published rules: high. Sources: 1256

Does Humic acid complexes help with hormones and fertility? What the studies show

We evaluated one meta-analysis or systematic review, 4 controlled studies and 3 further studies; the controlled studies include 232 participants in total. Result of the controlled studies: mostly improved. Strength of evidence under our published rules: high. Sources: 3678

Does Humic acid complexes help with energy, performance and fatigue? What the studies show

We evaluated 5 controlled studies and 6 further studies; the controlled studies include 415 participants in total. Result of the controlled studies: mostly improved. Strength of evidence under our published rules: high. Sources: 4678

Does Humic acid complexes help with inflammation and immune system? What the studies show

We evaluated 5 controlled studies and 12 further studies; the controlled studies include 567 participants in total. Result of the controlled studies: mixed. Strength of evidence under our published rules: moderate. Sources: 11131423

Does Humic acid complexes help with metabolism and blood sugar? What the studies show

We evaluated 3 controlled studies and 7 further studies; the controlled studies include 292 participants in total. Result of the controlled studies: mostly improved. Strength of evidence under our published rules: moderate. Sources: 47943

Does Humic acid complexes help with skin and wounds? What the studies show

We evaluated 3 controlled studies and 4 further studies; the controlled studies include 66 participants in total. Result of the controlled studies: mostly improved. Strength of evidence under our published rules: moderate. Sources: 12293042

What are humic acid complexes?

Humic acid complexes are mixtures of large organic molecules that form during the long decomposition of dead plant material, primarily from lignin. These include humic acids, fulvic acids and humins. Known forms are shilajit, humates, fulvic acid, drinkable peat and peat applications.

What effects do human studies show?

In men, testosterone increased under shilajit in three randomized studies 6722.

How safe are humic acid complexes?

The studies predominantly report good tolerability. More frequently mentioned were temporary skin redness and fatigue under mud and peat applications, briefly lasting burning under topical fulvic acid, as well as gastrointestinal complaints under a fulvic acid-containing drink. One case report describes an exercise-induced anaphylaxis in which shilajit was considered a co-trigger.

For which complaints are there no robust evidence?

For digestion and gut, two controlled studies are available that show no confirmed benefit 1823. For peat bath, drinkable peat and other humic acid complexes as a single preparation for fatigue, controlled data are lacking.

What should be considered when evaluating the studies?

Many studies are small and of short duration. The comparison conditions and the composition of the preparations differ considerably. Almost all studies on hormones and fertility tested shilajit in men; for women, hardly any robust data are available.

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Every statement on this page carries its evidence tier — proven, plausible or hypothesis — and leads to the original work. The decision in the individual case rests with the practitioner; we provide the connections.

International Health Research · https://ih-research.com/en/knowledge/huminsaeurekomplexe/ · Last updated: 2026-10-16