Humic Acid Complexes
Humic acid complexes are formed during the slow decomposition of plants, primarily from lignin; human studies show improvements mainly for shilajit and peat applications.
We evaluated 71 human studies on Humic acid complexes, including 19 randomised controlled trials and 3 meta-analyses or systematic reviews; the controlled studies include 1,611 participants in total. As of 3 October 2026.
1. What Is Humic Acid Complexes? Occurrence, Origin and Forms
Humic acid complexes are mixtures of large organic molecules that form when dead plant matter is broken down and transformed over long periods – above all lignin, the woody substance of plants. There is no single, uniform humic acid: origin, degree of maturation and extraction determine which molecules a preparation contains. They are divided into humic acids, fulvic acids and humins.
Humic acid complexes occur in soils, in peat and bog, in brown coal and leonardite, in compost and in rivers, lakes and their sediments. Shilajit, also called mumijo, is a resin-like substance that seeps from rock in high mountain ranges such as the Himalayas and the Altai and consists largely of humic substances.
Preparations taken by mouth are mostly obtained from leonardite, brown coal or peat: the humic substances are dissolved with alkali, separated and purified. Shilajit is purified and dried. There is also fulvic acid manufactured from carbohydrates (carbohydrate-derived fulvic acid, CHD-FA). Baths and packs use medicinal peat.
Forms and Preparations Studied
- Humic acids and humates, such as sodium or potassium humate
- Fulvic acid, including carbohydrate-derived fulvic acid (CHD-FA)
- Shilajit (mumijo, momiai, asphaltum, mineral pitch)
- Drinkable peat and peat extracts taken by mouth
- Peat baths, peat packs and peloids made from peat
- Combination products containing humic acid complexes – the other ingredients are named in each case
Not covered on this page:
- Sulphur, brine, radon and mineral baths without peat, and mineral mud (fango) without peat → Balneotherapy and Moor Therapy
- Humus as a soil parameter in agricultural and environmental studies
- Isolated lignin from the wood and paper industry
2. What Does Humic Acid Complexes Do? Results by Area
| Area | Result in controlled studies | Strength of evidence | Studies | Participants |
|---|---|---|---|---|
| Bones, joints and muscles | mostly improved | high | 1 meta-analyses · 11 controlled · 14 other | 584 |
| Hormones and fertility | mostly improved | high | 1 meta-analyses · 4 controlled · 3 other | 232 |
| Energy, performance and fatigue | mostly improved | high | 0 meta-analyses · 5 controlled · 6 other | 415 |
| Inflammation and immune system | mixed | moderate | 0 meta-analyses · 5 controlled · 12 other | 567 |
| Metabolism and blood sugar | mostly improved | moderate | 0 meta-analyses · 3 controlled · 7 other | 292 |
| Skin and wounds | mostly improved | moderate | 0 meta-analyses · 3 controlled · 4 other | 66 |
| Digestion and gut | mostly no difference | unclear | 0 meta-analyses · 1 controlled · 6 other | 0 |
| Brain and cognition | observational data only | unclear | 0 meta-analyses · 0 controlled · 4 other | 0 |
| Other outcomes | mostly improved | high | 0 meta-analyses · 12 controlled · 23 other | 1,055 |
How to read the table: counted are human studies whose results concern the area. “High” means at least one meta-analysis and two controlled studies showing improvement, or at least three controlled studies of which three quarters show improvement, with at least 300 participants in total. “Moderate” means at least two controlled studies showing improvement, as a majority, or one meta-analysis alongside controlled studies. “Low” means one controlled study showing improvement. Where an area has no controlled study, the strength of evidence is at most “low” (result “reviews only” or “observational data only”). Everything else is “unclear”. A study counts as showing improvement when at least half of its outcomes in this area improved. Reviews of combination products do not count as meta-analyses; results that only describe side effects or shares of users do not count as an effect. The same study is counted only once.
3. What the Studies Show in Detail
Humic Acid Complexes, Bones, Joints and Muscles: Human Studies
For bones, joints and muscles, peat applications relieved pain in controlled studies: in knee osteoarthritis under peat packs compared with a mere hot pack 19 and under peat compresses compared with a sham treatment 26, in back pain under peat pack plus trunk training compared with training alone 20. In another study on back pain, pain and mobility improved under peat therapy as well as under ultrasound and magnetic therapy; for pain, ultrasound performed best 27. A meta-analysis on mud therapy, which included peat in addition to clay and mineral mud, found less pain and better physical function 1. Under shilajit, muscle strength increased in randomized studies 6 and fatigue-related loss of strength decreased 21; after a tibial fracture, the bone healed faster under mumijo (Momiai) 5. Oral potassium humate relieved pain in knee osteoarthritis in a small randomized study 14. The strength of evidence is high, but many studies are small, and the comparison conditions as well as the composition of the preparations differ considerably.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 1 Balakrishna et al. 2026 | meta-analysis · 2,651 participants | Pelotherapy (mud, peat, clay, mineral-rich mud); Follow-up up to 6 months; vs. Sham, usual care, or no treatment | Pain post-intervention: improved (SMD -0.74; 95% CI -0.91 to -0.57); Pain at 3 months: improved (SMD -0.61; 95% CI -0.81 to -0.41); Pain at 6 months: improved (SMD -0.49; 95% CI -0.71 to -0.27) |
| 2 Richard et al. 2025 | systematic review | Balneotherapy: healing waters, peloids, peat packs, sepiolite clay; vs. heterogeneous controls, no meta-analysis possible | Pain: improved |
| 5 Seyed et al. 2020 | randomised controlled · 160 participants | Momiai (shilajit) capsules; two 500 mg capsules daily; 28 days; vs. Placebo | mean time to tibial bone union: improved (129 days in the experimental group, while it was 153 days in the placebo group (p < 0.049)) |
| 6 Divya et al. 2026 | randomised controlled · 100 participants | TruBlk™ Shilajit resin (≥60% fulvic acid, ≥10% shilarathenes™); 250 mg twice daily; 90 days; vs. Placebo, double-blind, randomised, multicentre | 1RM leg press: improved (+26.0% vs +18.4%; p=0.0003, d=0.74); muscle endurance: improved (+110.8% vs +80.5%; p=0.0017, d=0.60); delayed onset muscle soreness (DOMS): improved (p=0.036) |
| 8 Darshani et al. 2025 | randomised controlled · 66 participants | ShilAbsorb™ gummies (Shilajit plus herbs); two gummies daily; 60 days; vs. Placebo | Skeletal muscle mass: improved (4.47% more than placebo); Leg press 1RM: improved (p<0.001); Chest press 1RM: improved (p<0.001) |
| 14 C.E.J. et al. 2010 | randomised controlled · 28 participants | Potassium humate (from brown coal) vs. lactose; 600 mg three times daily; 6 weeks per phase, 14 weeks total; vs. Placebo (lactose), randomized double-blind crossover | WOMAC pain subscale: improved; WOMAC total and subscale scores: improved |
| 16 Neltner et al. 2024 | randomised controlled | Oral Shilajit supplementation; 500 mg/day or 1000 mg/day; 8 weeks; vs. Placebo | Serum pro-c1α1 (type 1 collagen synthesis): improved (Low dose: p = 0.008, d = 1.2; High dose: p = 0.007, d = 1.3); Proportion exceeding minimal clinically important difference: improved (p = 0.03) |
| 19 Myeongkyu et al. 2020 | randomised controlled | Peat pack applied to both knees; 20 minutes per session, 8 sessions over 5 days; 5 days; vs. Hot-pack-only control | Pain (VAS): improved (p < 0.001); Serum COMP: no difference; Gait velocity: improved (p = 0.002) |
Further studies in this area: 20 21 25 26 27 33 34 36 39 41 49 50 53 54 55 56 62 68
Humic Acid Complexes, Hormones and Fertility: Human Studies
In men, testosterone increased under shilajit in three randomized studies 6722; a systematic review classifies shilajit as possibly effective in men with late-onset hypogonadism 3. One study also found a better sexual response 7, another an increase in DHEAS with unchanged levels of LH and FSH 22. A mixed preparation of shilajit with ashwagandha, ginger, black pepper, Mucuna pruriens and akarkara also improved free and total testosterone in a randomized controlled study 8. The strength of evidence is high, but the studies tested almost exclusively shilajit in men; for peat bath, drinkable peat and other humic acid complexes as well as for women, hardly any robust data are available.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 3 Morgado et al. 2024 | systematic review | 27 testosterone boosters, including purified Shilajit extract (PrimaVie™); vs. Placebo | Serum total testosterone: improved (possibly effective) |
| 6 Divya et al. 2026 | randomised controlled · 100 participants | TruBlk™ Shilajit resin (≥60% fulvic acid, ≥10% shilarathenes™); 250 mg twice daily; 90 days; vs. Placebo, double-blind, randomised, multicentre | free testosterone: improved (+21.8% vs −2.9%; p=0.030, d=0.45); total testosterone: improved (+15.6% vs −3.8%; p=0.038, d=0.43) |
| 7 Darshani et al. 2025 | randomised controlled · 66 participants | ShilAbsorb™ gummies (Shilajit); 90 days; vs. placebo | total testosterone: improved (25.39% increase); free testosterone: improved (9.51% increase); sexual response (orgasm scores): improved (17.59% greater improvement) |
| 8 Darshani et al. 2025 | randomised controlled · 66 participants | ShilAbsorb™ gummies (Shilajit plus herbs); two gummies daily; 60 days; vs. Placebo | Free testosterone: improved (10.33%); Total testosterone: improved (9.34%); Cortisol: improved (26.5%) |
| 22 S et al. 2015 | randomised controlled | Purified Shilajit (Ayurvedic rasayana); 250 mg twice a day; 90 consecutive days; vs. Placebo, randomised, double-blind | Total testosterone: improved (P < 0.05); Free testosterone: improved (P < 0.05); DHEAS: improved (P < 0.05) |
| 40 Tuhin et al. 2010 | study · 35 participants | Processed Shilajit (PS), capsule; 100 mg twice daily after major meals; 90 days; vs. Before-after comparison, no control group | Total sperm count: improved (+61.4%); Spermia: improved (+37.6%); Motility: improved (12.4-17.4% after different time intervals) |
| 66 R. et al. 2020 | review | Shilajit with Triphala Kwath | management of hypothyroidism: unclear |
| 68 Beer et al. 2013 | review | Therapeutic peat (peloid) | Therapeutic use of peat for fertility treatment: unclear |
Humic Acid Complexes, Energy, Performance and Fatigue: Human Studies
In two randomized studies in men, shilajit improved muscular endurance and lowered perceived exertion 6; in the other, maximal oxygen uptake increased, and fatigue decreased somewhat more than under placebo 7. A mixed preparation of shilajit and herbs improved endurance in strength exercises 8. The strength of evidence is high, but the controlled studies predominantly tested shilajit alone or in mixtures, mostly included healthy, trained men and were partly small; for humic acids, fulvic acid, drinkable peat or medicinal peat as a single preparation for fatigue, controlled data are lacking.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 4 Victoria et al. 2025 | randomised controlled · 166 participants | Placebo, PE 500 mg, PE 1000 mg, chromium 400 µg with 6 mg PE and 6 mg shilajit, chromium 800 µg with 12 mg PE and 12 mg shilajit; shilajit 6 mg/day (Cr-400) or 12 mg/day (Cr-800), once daily; 12 weeks; vs. placebo, parallel, double-blind, randomized | body composition, strength, and aerobic capacity: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10) |
| 6 Divya et al. 2026 | randomised controlled · 100 participants | TruBlk™ Shilajit resin (≥60% fulvic acid, ≥10% shilarathenes™); 250 mg twice daily; 90 days; vs. Placebo, double-blind, randomised, multicentre | rating of perceived exertion (RPE): improved (p=0.002); VO₂max: improved (+3.8% vs +2.9%; p=0.032, d=0.41) |
| 7 Darshani et al. 2025 | randomised controlled · 66 participants | ShilAbsorb™ gummies (Shilajit); 90 days; vs. placebo | VO2 max: improved (5.92%); Fatigue Severity Scale: improved (4.14% greater reductions) |
| 8 Darshani et al. 2025 | randomised controlled · 66 participants | ShilAbsorb™ gummies (Shilajit plus herbs); two gummies daily; 60 days; vs. Placebo | Endurance (repetitions at 50% 1RM), chest: improved (7.65%); Endurance (repetitions at 50% 1RM), leg: improved (3.17%); Perceived exertion (RPE): improved |
| 15 Gonzalez et al. 2020 | randomised controlled · 17 participants | multi-ingredient preworkout supplement with ancient peat and apple extracts; single dose, one hour before sprint protocol; vs. placebo, randomized, double-blind, counterbalanced | average power across repeated sprints: improved (PAVG (75-229 W)); peak power across repeated sprints: improved (PPK (79-209 W)); average velocity across repeated sprints: no difference (2.34-5.87 m·s, p ≤ 0.002) |
| 37 Stier-Jarmer et al. 2017 | study · 78 participants | moor bath (moor application); 42 °C, 20 min, followed by 20 min rest; 7 applications over 3 weeks; vs. pre-post comparison without control group | salivary cortisol: improved (Z = -3.355, p = 0.0008); salivary cortisol in week 3: no difference (non-significant decrease) |
| 41 Divya et al. 2026 | study · 25 participants | TruBlk™ Shilajit Resin; 500 mg/day (250 mg twice daily); 28 days; vs. no control group (open-label single-arm) | Fatigue Severity Scale: improved (decreased by 32.40% (p < 0.001)); rating of perceived exertion: improved (decreased by 23.63% (p < 0.001)); maximal oxygen uptake (VO₂ max): improved (+1.36%, p < 0.001) |
| 55 Dr. et al. 2025 | review | standardized Shilajit extracts (Asphaltum punjabianum); 250-500 mg/day; vs. no uniform comparator; review of preclinical and clinical studies | fatigue resistance: improved |
Further studies in this area: 57 63 69
Humic Acid Complexes, Inflammation and Immune System: Human Studies
In hay fever and atopy, skin test reactions weakened in two small randomized studies, with fulvic acid (CHD-FA) 13 and with oral potassium humate 11; in the potassium humate study, the eosinophil count also decreased, while immune cell functions such as neutrophil adhesion and basophil stimulation remained unchanged 11. The strength of evidence is moderate: the controlled studies are small, some without a placebo group, and the larger investigations concern combination preparations or other diseases. Oral humates and fulvic acid, peat applications, and mixtures were studied; for peat baths, drinkable peat, and shilajit as a single preparation, predominantly uncontrolled observations are available, and a case report describes an exercise-induced anaphylaxis in which shilajit was considered a co-trigger 44.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 11 Justin et al. 2008 | randomised controlled · 40 participants | oral potassium humate; vs. random assignment, no placebo group reported | skin prick test: improved (significant decrease); eosinophil counts: improved (significant decrease); neutrophil adhesion: no difference (No significant differences) |
| 13 Justin et al. 2012 | randomised controlled · 30 participants | carbohydrate-derived fulvic acid (CHD-FA), 3.8%; 5–40 mL escalating; 20 or 40 mL twice daily; 3 days or 1 week each, with washout; vs. placebo, double-blind, crossover | skin prick test response: improved (significant decrease) |
| 14 C.E.J. et al. 2010 | randomised controlled · 28 participants | Potassium humate (from brown coal) vs. lactose; 600 mg three times daily; 6 weeks per phase, 14 weeks total; vs. Placebo (lactose), randomized double-blind crossover | hs-CRP: improved |
| 23 M. et al. 2018 | controlled · 332 participants | CHD-FA in wellness drink F0210; vs. placebo, double-blind, parallel | time to ART indication (event): no difference (p = 0.5724); CD4 count: unclear; HIV-1 viral load: unclear |
| 24 Strelis et al. 1991 | controlled · 137 participants | Peloidin phonophoresis, humisol injections, torfotum injections; vs. Control group without mud preparations | cellular immunity indices: improved; immunoglobulins G: improved |
| 40 Tuhin et al. 2010 | study · 35 participants | Processed Shilajit (PS), capsule; 100 mg twice daily after major meals; 90 days; vs. Before-after comparison, no control group | Pus and epithelial cell count: improved |
| 41 Divya et al. 2026 | study · 25 participants | TruBlk™ Shilajit Resin; 500 mg/day (250 mg twice daily); 28 days; vs. no control group (open-label single-arm) | C-reactive protein (CRP): improved (declined by 25.35% (p = 0.023)) |
| 42 N. et al. 2026 | case series · 20 participants | fulvic acid-based gel; 21 days topical application, assessment until day 28 | Inflammation area by autofluorescence stomatoscopy: improved (significant reduction) |
Further studies in this area: 44 46 47 49 51 57 60 62 64
Humic Acid Complexes, Metabolism and Blood Sugar: Human Studies
A randomized study with shilajit gummies found no difference in body weight, BMI, and waist circumference 7. A study with a mixture of shilajit and agnimantha showed a lower body mass (BMI) and lower total cholesterol compared with another herbal preparation 9. The strength of evidence is moderate; it remains open whether the effects are due solely to the humic acid complexes and whether they can be confirmed in healthy people.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 4 Victoria et al. 2025 | randomised controlled · 166 participants | Placebo, PE 500 mg, PE 1000 mg, chromium 400 µg with 6 mg PE and 6 mg shilajit, chromium 800 µg with 12 mg PE and 12 mg shilajit; shilajit 6 mg/day (Cr-400) or 12 mg/day (Cr-800), once daily; 12 weeks; vs. placebo, parallel, double-blind, randomized | insulin sensitivity: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10); blood lipid profiles: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10) |
| 7 Darshani et al. 2025 | randomised controlled · 66 participants | ShilAbsorb™ gummies (Shilajit); 90 days; vs. placebo | body weight, BMI, waist circumference: no difference |
| 9 Eranga et al. 2026 | randomised controlled · 60 participants | Agnimantha Shilajit Yoga (AS) vs. Bilvadi Yoga (BY); AS 0.5 g twice daily; BY 5 g twice daily with 10 mL honey; vs. AS vs. BY (Bilvadi Yoga) | Body mass index: improved (Decreased from 3.60 to 2.00 (p < 0.001)); Total cholesterol: improved (reduced from 244.68 to 189.04) |
| 43 Singh et al. 2025 | case report · 1 participants | Shilajatu Darvi Yoga: Shilajit plus Berberis aristata decoction; 5 mL twice daily with warm water, empty stomach; 3 months | HbA1c: improved (12.8 to 7.3); fasting blood sugar: improved (224 to 122); postprandial blood sugar: improved (437 to 149) |
| 48 Sharma et al. 2003 | study | Shilajit; 2 g daily; 45 days | serum triglycerides: improved; serum cholesterol: improved; HDL cholesterol: improved |
| 49 Н. et al. 2000 | study | Sodium humate balneotherapy; low concentration of the preparation | lipid modulating effect: improved; metabolic processes: improved |
| 52 Sakshi et al. 2026 | review | Arogyavardhini Vati, Ayurvedic herbo-mineral formulation containing Shilajit | Lipid metabolism: improved |
| 54 Ashif et al. 2025 | review | Shilajit (Asphaltum Punjabianum), purified; well tolerated even at very high doses; several weeks of continuous intake; vs. no comparison; myths checked against evidence | metabolic processes: improved |
Further studies in this area: 57 58
Humic Acid Complexes, Skin and Wounds: Human Studies
In eczema, the investigators assessed the response with fulvic acid (CHD-FA) for topical application as better than with a plain care cream in a small randomized study; however, severity and redness improved in both groups 12. A controlled, non-randomized study with oral shilajit found better skin blood flow and altered activity of genes for connective tissue and vessels in middle-aged women 30. The strength of evidence is moderate; the studies are small, and the shilajit study is not randomized. It remains open whether the findings apply to other preparations and over longer periods.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 12 Justin et al. 2011 | randomised controlled · 36 participants | topical CHD-FA versus placebo (emollient); twice daily; four weeks; vs. placebo/emollient therapy | eczema severity: improved; erythema: improved; scaling: improved |
| 29 Rondanelli et al. 2012 | controlled · 30 participants | Association of Massaciuccoli peat and sodium chloride water of Undulna Thermae; 2 weeks; vs. Intervention group versus control (not further described) | skin elasticity: improved (+5.52%, p < 0.001); subcutaneous perfusion: improved |
| 30 Amitava et al. 2019 | controlled | oral shilajit supplement; 125 or 250 mg bid; 14 weeks; vs. placebo and baseline | skin perfusion: improved; expression of ECM and vascular genes: improved |
| 42 N. et al. 2026 | case series · 20 participants | fulvic acid-based gel; 21 days topical application, assessment until day 28 | Complete epithelialization of erosions: improved (92% of patients by day 28) |
| 56 Aleksander et al. 2025 | review | peat and sapropel peloids containing humic, fulvic, hymatomelanic acids; vs. classical thermal versus non-thermal pelotherapy techniques | effectiveness in skin disorders: improved |
| 62 Tian et al. 2022 | review | Mud (raw and refined clay) | Glutathione enzyme and superoxide dismutase activity in skin: improved; Skin microbial community: improved; Skin drug delivery: improved |
| 67 Varsha et al. 2019 | review | Fulvic acid as topical cream/lotion in a moisturizing base; vs. Emollients alone | Effectiveness in skin inflammation: improved; Tolerance |
Humic Acid Complexes, Digestion and Gut: Human Studies
For digestion and the gut, two controlled studies are available. In people with diarrhea-predominant irritable bowel syndrome, a randomized study found no confirmed difference from placebo with humic acids 18. Women responded better than men 18. A wellness drink with fulvic acid (CHD-FA) was overall well tolerated in a controlled study of 332 HIV-positive people 23. However, gastrointestinal complaints occurred more frequently with it than with placebo 23. The strength of evidence is overall unclear, as the controlled findings do not give a consistent picture. Reliable statements about digestive complaints cannot be derived from this.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 18 Ingolf et al. 2021 | randomised controlled | Humic acids versus placebo; vs. Placebo, double-blind, randomised | IBS symptom severity (IBS-SSS), main effect of treatment: no difference (F=1.56, p=0.221); Response rate (≥50-point improvement on IBS-SSS): no difference (57.9% vs. 36.8%, p=0.194); Response rate women vs. men on humic acids: improved (71.4% vs. 20.0%, p=0.045) |
| 23 M. et al. 2018 | controlled · 332 participants | CHD-FA in wellness drink F0210; vs. placebo, double-blind, parallel | gastrointestinal intolerance |
| 45 Shkliaev et al. 2011 | case series | SMC electrophoresis combined with peloidotherapy (Uva peat muds) | proliferative activity of duodenal epithelium: improved |
| 52 Sakshi et al. 2026 | review | Arogyavardhini Vati, Ayurvedic herbo-mineral formulation containing Shilajit | Liver function: improved |
| 56 Aleksander et al. 2025 | review | peat and sapropel peloids containing humic, fulvic, hymatomelanic acids; vs. classical thermal versus non-thermal pelotherapy techniques | effectiveness in digestive system diseases: improved |
| 61 Paul et al. 2023 | review | Ingredients containing fulvic acids and/or humic acids; Long-term use | Adverse events from fulvic/humic acid ingredients |
| 62 Tian et al. 2022 | review | Mud (raw and refined clay) | Gastrointestinal tract protection and treatment of gastrointestinal diseases: improved |
Humic Acid Complexes, Brain and Cognition: Human Studies
For the brain and mental performance, only observations without a control group are available for humic acid complexes. A study without a comparison group reports a better mood after rhythmic rubbing with Solum oil, a peat extract with lavender oil 35. Another study reports a better mood after a peat bath 37. Two review articles suggest benefits for mental performance from shilajit 54 and in neurodegenerative diseases from fulvic acid 64. Since no controlled studies and no meta-analyses are available, the strength of evidence is unclear; a peat extract-lavender oil mixture, a peat bath, shilajit, and fulvic acid were studied.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 35 Thomas et al. 2008 | study · 100 participants | Solum Oil: aqueous peat extract (1:5) 1.96 g and lavender oil 0.5 g per 10 g; 3 treatments within 24 days; 24 days; vs. no control group, pre-post comparison | Mood (Bf-S): improved (25.8 (95% CI; 22.8-28.1) to 13.3 (95% CI; 11.7-15.0)) |
| 37 Stier-Jarmer et al. 2017 | study · 78 participants | moor bath (moor application); 42 °C, 20 min, followed by 20 min rest; 7 applications over 3 weeks; vs. pre-post comparison without control group | mood state (Multidimensional Mood State Questionnaire): improved (improved significantly) |
| 54 Ashif et al. 2025 | review | Shilajit (Asphaltum Punjabianum), purified; well tolerated even at very high doses; several weeks of continuous intake; vs. no comparison; myths checked against evidence | cognitive enhancement: improved |
| 64 Didiek et al. 2021 | review | Fulvic acid (FA), extracted from lignite, peat, bog and compost | combating neurodegenerative disorders: improved (highly promising results) |
Humic Acid Complexes: Further Outcomes in Studies
After disc surgery, everyday resilience (Oswestry index) improved with peat mud applications 25, and in knee osteoarthritis, general health status improved with peat compresses 26. With shilajit, perceived stress 7 and signs of oxidative stress 10 decreased, and with mumijo, a lowered platelet count was less common 28. A randomized study with shilajit also showed lower muscle damage values (creatine kinase, lactate dehydrogenase) 6; with potassium humate, the liver value GGT temporarily rose in four participants, and with placebo in two 14. A meta-analysis on mud therapy, which also included peat, found no increase in serious adverse events 1. The strength of evidence is overall high, as several controlled studies are available; shilajit, mumijo, fulvic acid (CHD-FA), potassium humate, and peat applications were tested, some in combination preparations. The transferability to other humic acid complexes and the confirmation of the safety findings in larger, longer-term studies remain open.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 1 Balakrishna et al. 2026 | meta-analysis · 2,651 participants | Pelotherapy (mud, peat, clay, mineral-rich mud); Follow-up up to 6 months; vs. Sham, usual care, or no treatment | Serious adverse events (RR 0.98; 95% CI 0.61-1.58) |
| 2 Richard et al. 2025 | systematic review | Balneotherapy: healing waters, peloids, peat packs, sepiolite clay; vs. heterogeneous controls, no meta-analysis possible | Health-related quality of life: improved |
| 4 Victoria et al. 2025 | randomised controlled · 166 participants | Placebo, PE 500 mg, PE 1000 mg, chromium 400 µg with 6 mg PE and 6 mg shilajit, chromium 800 µg with 12 mg PE and 12 mg shilajit; shilajit 6 mg/day (Cr-400) or 12 mg/day (Cr-800), once daily; 12 weeks; vs. placebo, parallel, double-blind, randomized | pulse wave velocity: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10); flow-mediated dilation: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10); platelet aggregation: improved (p < 0.05 or approaching significance, p > 0.05 to p < 0.10) |
| 6 Divya et al. 2026 | randomised controlled · 100 participants | TruBlk™ Shilajit resin (≥60% fulvic acid, ≥10% shilarathenes™); 250 mg twice daily; 90 days; vs. Placebo, double-blind, randomised, multicentre | creatine kinase: improved (−33.6% vs −6.9%; p=0.030, δ=−0.26); lactate dehydrogenase: improved (−17.8% vs −4.2%; p=0.039, δ=−0.24) |
| 7 Darshani et al. 2025 | randomised controlled · 66 participants | ShilAbsorb™ gummies (Shilajit); 90 days; vs. placebo | Perceived Stress Scale-10: improved (3.62% greater reductions) |
| 9 Eranga et al. 2026 | randomised controlled · 60 participants | Agnimantha Shilajit Yoga (AS) vs. Bilvadi Yoga (BY); AS 0.5 g twice daily; BY 5 g twice daily with 10 mL honey; vs. AS vs. BY (Bilvadi Yoga) | Subjective symptoms (pendulous body movements, heaviness, perspiration, thirst, hunger): improved (p < 0.001); Liver enzymes (AST, ALT, ALP): improved (p < 0.001); Creatinine: improved (p < 0.001) |
| 10 Satish et al. 2023 | randomised controlled · 60 participants | Purified shilajit (Asphaltum punjabianum); 500 mg twice daily; 30 days; vs. Shilajit plus antihypertensives vs antihypertensives alone | Malondialdehyde: improved (P < 0.001); Oxidised low-density lipoproteins: improved (P = 0.015); Total antioxidant capacity: improved (P = 0.002) |
| 13 Justin et al. 2012 | randomised controlled · 30 participants | carbohydrate-derived fulvic acid (CHD-FA), 3.8%; 5–40 mL escalating; 20 or 40 mL twice daily; 3 days or 1 week each, with washout; vs. placebo, double-blind, crossover | safety parameters (ECG, laboratory, examination) (remained constant throughout the trial) |
Further studies in this area: 14 17 23 25 26 28 29 31 32 34 35 38 40 41 42 43 46 48 51 54 56 57 59 63 64 65 66
4. How Is Humic Acid Complexes Dosed? Preparation, Dose and Duration in Studies
The studies investigated mainly shilajit as capsules, gummies or resin, peat applications as baths, packs and peloids, as well as oral humates and fulvic acid. Some preparations were mixtures, such as shilajit with herbs or fulvic acid in a wellness drink. The doses and application durations are shown in the table.
| Preparation or form | Dose | Duration | Study |
|---|---|---|---|
| Placebo, PE 500 mg, PE 1000 mg, chromium 400 µg with 6 mg PE and 6 mg shilajit, chromium 800 µg with 12 mg PE and 12 mg shilajit | shilajit 6 mg/day (Cr-400) or 12 mg/day (Cr-800), once daily | 12 weeks | 4 |
| Momiai (shilajit) capsules | two 500 mg capsules daily | 28 days | 5 |
| TruBlk™ Shilajit resin (≥60% fulvic acid, ≥10% shilarathenes™) | 250 mg twice daily | 90 days | 6 |
| ShilAbsorb™ gummies (Shilajit) | — | 90 days | 7 |
| ShilAbsorb™ gummies (Shilajit plus herbs) | two gummies daily | 60 days | 8 |
| Agnimantha Shilajit Yoga (AS) vs. Bilvadi Yoga (BY) | AS 0.5 g twice daily; BY 5 g twice daily with 10 mL honey | — | 9 |
| Purified shilajit (Asphaltum punjabianum) | 500 mg twice daily | 30 days | 10 |
| topical CHD-FA versus placebo (emollient) | twice daily | four weeks | 12 |
| carbohydrate-derived fulvic acid (CHD-FA), 3.8% | 5–40 mL escalating; 20 or 40 mL twice daily | 3 days or 1 week each, with washout | 13 |
| Potassium humate (from brown coal) vs. lactose | 600 mg three times daily | 6 weeks per phase, 14 weeks total | 14 |
| multi-ingredient preworkout supplement with ancient peat and apple extracts | — | single dose, one hour before sprint protocol | 15 |
| Oral Shilajit supplementation | 500 mg/day or 1000 mg/day | 8 weeks | 16 |
| Aviron Rapid, dietary supplement containing andrographolide, spirulina and humic acid | — | 5 days (adolescents) and 7 days (children) | 17 |
| Peat pack applied to both knees | 20 minutes per session, 8 sessions over 5 days | 5 days | 19 |
| Mud pack plus core exercise | Mud pack 30 min, core exercise 50 min, twice daily | 4 days, 8 sessions | 20 |
5. Is Humic Acid Complexes Safe? Side Effects in Studies
The studies predominantly report good tolerability. More frequently mentioned were temporary skin redness and fatigue under mud and peat applications, briefly lasting burning under topical fulvic acid, as well as gastrointestinal complaints under a fulvic acid-containing drink. One case report describes an exercise-induced anaphylaxis in which shilajit was considered a co-trigger, and in one study the liver value GGT temporarily increased under potassium humate in four and under placebo in two participants.
| Study | Reported side effects |
|---|---|
| 1 Balakrishna et al. 2026 | Skin erythema 6.5%, transient fatigue 4.8%; no increase in serious adverse events |
| 5 Seyed et al. 2020 | no significant difference between groups (p = 0.839) |
| 6 Divya et al. 2026 | No adverse events recorded in the active group |
| 7 Darshani et al. 2025 | no adverse events reported |
| 8 Darshani et al. 2025 | Safety assessed, no details in abstract |
| 11 Justin et al. 2008 | safety assessed via blood and nasal samples |
| 12 Justin et al. 2011 | short-lived burning sensation on application, otherwise no difference |
| 13 Justin et al. 2012 | no severe adverse events; safety parameters constant |
| 14 C.E.J. et al. 2010 | GGT increase (4 vs. 2), normalized after discontinuation; tolerability good |
| 17 Rada et al. 2023 | Low number of adverse events, no major differences between groups |
| 18 Ingolf et al. 2021 | No adverse events reported; no patient discontinued |
| 23 M. et al. 2018 | gastrointestinal intolerance (diarrhoea, nausea, vomiting) more frequent than placebo |
6. What Remains Open: Limits of the Evidence
- Many studies are small and of short duration.
- The comparison conditions and the composition of the preparations differ considerably.
- For peat bath, drinkable peat and other humic acid complexes as a single preparation for fatigue, controlled data are lacking.
- Almost all studies on hormones and fertility tested shilajit in men; for women, hardly any robust data are available.
- It remains open whether the effects are due solely to the humic acid complexes or to other components of mixed preparations.
7. Bottom Line: What Is Established About Humic Acid Complexes
Humic acid complexes are not a uniform substance but mixtures of large organic molecules from decomposed plant material, primarily from lignin. Human studies show improvements for shilajit and peat applications in pain, physical function, muscle strength, testosterone, endurance performance and some skin and immune parameters. The strength of evidence is high for bones, joints and muscles, hormones as well as energy and performance, moderate for metabolism, skin and immune system, and unclear for digestion as well as brain. Many studies are small, the preparations differ greatly, and controlled data are lacking for several preparations.
Frequently Asked Questions
How well has Humic acid complexes been studied in humans?
We evaluated 71 human studies on Humic acid complexes, including 19 randomised controlled trials and 3 meta-analyses or systematic reviews; the controlled studies include 1,611 participants in total. As of 3 October 2026.
Does Humic acid complexes help with bones, joints and muscles? What the studies show
Does Humic acid complexes help with hormones and fertility? What the studies show
Does Humic acid complexes help with energy, performance and fatigue? What the studies show
Does Humic acid complexes help with inflammation and immune system? What the studies show
Does Humic acid complexes help with metabolism and blood sugar? What the studies show
Does Humic acid complexes help with skin and wounds? What the studies show
What are humic acid complexes?
Humic acid complexes are mixtures of large organic molecules that form during the long decomposition of dead plant material, primarily from lignin. These include humic acids, fulvic acids and humins. Known forms are shilajit, humates, fulvic acid, drinkable peat and peat applications.
What effects do human studies show?
How safe are humic acid complexes?
The studies predominantly report good tolerability. More frequently mentioned were temporary skin redness and fatigue under mud and peat applications, briefly lasting burning under topical fulvic acid, as well as gastrointestinal complaints under a fulvic acid-containing drink. One case report describes an exercise-induced anaphylaxis in which shilajit was considered a co-trigger.
For which complaints are there no robust evidence?
What should be considered when evaluating the studies?
Many studies are small and of short duration. The comparison conditions and the composition of the preparations differ considerably. Almost all studies on hormones and fertility tested shilajit in men; for women, hardly any robust data are available.
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Every statement on this page carries its evidence tier — proven, plausible or hypothesis — and leads to the original work. The decision in the individual case rests with the practitioner; we provide the connections.