Meta-Analysis: Mediterranean Diet Linked to Lower hs-CRP, IL-6 and IL-17
A systematic review and meta-analysis of randomized controlled trials found that the Mediterranean diet improved certain inflammation biomarkers, particularly hs-CRP, IL-6 and IL-17, compared with a control diet. No significant effects were noted for CRP, IL-10, tumor necrosis factor-alpha or total antioxidant capacity. Subgroup analyses showed stronger effects for specific age groups and intervention durations.
1. What the Research Says
Systematic review and meta-analysis of randomized controlled trials in adults. It reports biomarker changes, and the authors call for further high-quality studies to confirm the findings.
2. How It Fits Earlier Research
The finding fits with earlier work: the Mediterranean diet can lower some inflammation markers while others remain unchanged. This matches the picture already seen in reviews and controlled studies. The Mediterranean diet, its components, and cardiovascular disease. (2015) · Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms. (2018) · Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults: The ATTICA Study. (2004)
3. Source
Full evidence overview: Mediterranean Diet
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