Ginger (Zingiber Officinale)
Ginger is the rhizome of Zingiber officinale; human studies show relief for nausea, osteoarthritis and metabolic values.
We evaluated 211 human studies on Ginger (Zingiber officinale), including 96 randomised controlled trials and 55 meta-analyses or systematic reviews; the controlled studies include 7,918 participants in total. As of 7 October 2026.
1. What Is Ginger (Zingiber Officinale)? Occurrence, Origin and Forms
Ginger is the rhizome of the plant Zingiber officinale, a member of the ginger family (Zingiberaceae). The plant is cultivated in tropical and subtropical regions, and its aromatic, pungent rhizome has long served as a spice and as a traditional remedy for digestive complaints, nausea and colds. In studies, ginger is examined as fresh or dried rhizome, as powder, as an extract or as essential oil.
Ginger grows as a herbaceous perennial in warm, humid climates and is cultivated mainly in Asia, Africa and Latin America. The part used is the underground rhizome, which reaches the market fresh, dried or further processed.
After harvest the rhizome is washed and then used fresh, dried and ground, or processed into extracts; its pungency comes from gingerols and shogaols, which often serve as markers of the preparation in studies. Preparations examined include dried powder, aqueous and alcoholic extracts, standardized extracts and the essential oil.
Forms and Preparations Studied
- fresh rhizome
- dried rhizome and powder
- aqueous extract (infusion, tea)
- alcoholic or standardized extract
- essential oil
Not covered on this page:
- Galangal (Alpinia galanga) and other members of the ginger family such as turmeric (Curcuma longa)
- Wild ginger (Asarum species), an unrelated plant with a similar name
- other Zingiber species such as Zingiber zerumbet
- ginger flavouring and ginger-containing soft drinks that contain no rhizome
2. What Does Ginger (Zingiber Officinale) Do? Results by Area
| Area | Result in controlled studies | Strength of evidence | Studies | Participants |
|---|---|---|---|---|
| Nausea and vomiting, including pregnancy | mostly improved | high | 10 meta-analyses · 7 controlled · 6 other | 467 |
| Blood glucose and metabolism | mostly improved | high | 8 meta-analyses · 9 controlled · 10 other | 591 |
| Chemotherapy-induced nausea | mostly no difference | high | 4 meta-analyses · 6 controlled · 3 other | 909 |
| Osteoarthritis | mostly improved | high | 3 meta-analyses · 2 controlled · 7 other | 220 |
| Digestion and gastrointestinal complaints | mostly improved | high | 2 meta-analyses · 3 controlled · 5 other | 331 |
| Menstrual pain | reviews only | low | 1 meta-analyses · 0 controlled · 0 other | 0 |
| Other investigations | mostly improved | high | 14 meta-analyses · 50 controlled · 52 other | 3,479 |
How to read the table: counted are human studies whose results concern the area. “High” means at least one meta-analysis and two controlled studies showing improvement, or at least three controlled studies of which three quarters show improvement, with at least 300 participants in total. “Moderate” means at least two controlled studies showing improvement, as a majority, or one meta-analysis alongside controlled studies. “Low” means one controlled study showing improvement. Where an area has no controlled study, the strength of evidence is at most “low” (result “reviews only” or “observational data only”). Everything else is “unclear”. A study counts as showing improvement when at least half of its outcomes in this area improved. Reviews of combination products do not count as meta-analyses; results that only describe side effects or shares of users do not count as an effect. The same study is counted only once.
3. What the Studies Show in Detail
Ginger (Zingiber Officinale), Nausea and Vomiting, Including Pregnancy: Human Studies
In pregnant women, ginger alleviated nausea compared with placebo, the number of vomiting episodes did not fall with certainty 9. Two further reviews rate ginger capsules and ginger in general as effective against nausea in pregnancy 4448. An umbrella review and a meta-analysis found less nausea and vomiting, with nausea responding more clearly 2032. Capsules, powder or biscuits were examined 32, in one review fresh rhizome 50. After thyroid operations, inhaling essential ginger oil lowered the severity of pain and nausea compared with usual care 121. A standardized extract, added to a carbohydrate drink before anesthesia, reduced the number of vomiting episodes after brain tumor operations, but not the frequency of nausea and vomiting 97. In children with vomiting due to acute gastroenteritis, fewer children vomited again after oral ginger administration than with placebo 68. It remains open which preparation and dose works best in which baseline situation.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 2 Guo et al. 2026 | meta-analysis · 8,275 participants | ginger (form/preparation not reported); vs. eight other nonpharmacological interventions | PONV VAS severity: improved (ginger was most effective (29%)) |
| 6 Wang et al. 2025 | meta-analysis · 2,062 participants | ginger as one of 15 plant substances; vs. standard treatment and other plant substances | nausea: unclear |
| 9 Viljoen et al. 2014 | systematic review · 1,278 participants | orally administered ginger (form not specified in abstract); Subgroup analysis: lower daily dose <1500 mg favored; vs. placebo or vitamin B6 | improvement of nausea symptoms: improved (MD 1.20, 95% CI 0.56-1.84, p = 0.0002); number of vomiting episodes: no difference (MD 0.72, 95% CI -0.03-1.46, p = 0.06); spontaneous abortion versus placebo: no difference (RR 3.14, 95% CI 0.65-15.11, p = 0.15) |
| 20 Tahergorabi et al. 2026 | systematic review | Ginger supplements; usually 450 to 1950 mg daily; vs. placebo, vitamin B6 or traditional medications | severity and occurrence of nausea and vomiting: improved; nausea (more noticeable than for vomiting): improved; adverse effects (spontaneous abortion, heartburn, drowsiness) |
| 25 Paudel et al. 2025 | systematic review | Ginger supplements (form not specified); 1-3 g/day; for NVP 500-1,500 mg/day in divided doses; vs. Placebo/control (from meta-analyses) | nausea symptoms: improved; vomiting frequency: no difference |
| 29 Rondanelli et al. 2025 | systematic review | Ginger as herbal supplement, form not specified; vs. no comparison; review of dietary strategies | nausea and vomiting during pregnancy: unclear |
| 32 Gao et al. 2025 | meta-analysis | Ginger as capsules, powders or biscuits; vs. Placebo, vitamin B6 or metoclopramide | nausea and vomiting symptoms: improved (pooled odds ratio of 0.41 (95% CI: 0.22-0.79, P = 0.008)) |
| 33 Choi et al. 2025 | systematic review | Traditional East Asian Medicine, including ginger and herbal decoctions | Alleviation of nausea and vomiting in pregnancy: improved |
Further studies in this area: 35 44 48 50 53 66 68 97 104 105 113 121 135 171 176
Ginger (Zingiber Officinale), Blood Glucose and Metabolism: Human Studies
Compared with placebo, ginger lowered fasting blood glucose in type 2 diabetes 96, fatty liver 98, metabolic syndrome 106 and gestational diabetes 86; it lowered the long-term blood glucose HbA1c in type 2 diabetes 96. Insulin resistance fell compared with placebo in fatty liver, metabolic syndrome and gestational diabetes 8698106; in women with PCOS, cinnamon and metformin lowered it, ginger did not 77. Triglycerides fell compared with placebo in metabolic syndrome 106 and with an extract of steamed ginger in overweight, there also total cholesterol 78. In fatty liver, total and LDL cholesterol fell, but not triglycerides 98; in type 2 diabetes the individual blood lipids did not change 96. In gestational diabetes, ginger tablets additionally lowered fasting insulin, but not blood glucose two hours after eating 86. An aqueous extract reduced the blood glucose rise after a sugar solution in non-diabetic adults 115. The findings are based predominantly on dried rhizome and powder; most studies were small and short.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 1 Musazadeh et al. 2026 | systematic review · 43,570 participants | Ginger supplementation (form not specified); vs. Control in the included meta-analyses | Fasting blood sugar: improved (WMD: - 0.68 to - 18.81 mg/dL); HbA1c: improved (WMD: - 0.27 to - 1.66%); HOMA-IR: improved (WMD: - 0.54 to - 1.67) |
| 13 Abdulla et al. 2025 | meta-analysis · 315 participants | Antioxidant adjuncts including ginger, added to nonsurgical periodontal therapy; vs. Nonsurgical periodontal therapy alone or other antioxidants | HbA1c: improved |
| 16 Chen et al. 2026 | meta-analysis | Ginger supplementation (form not specified); vs. Placebo | Fasting blood sugar: improved (MD -16.27 mg/dl, 95% CI (-25.75, -6.80)); Hemoglobin A1c: improved (MD -0.41%, 95% CI (-0.63, -0.20)); HOMA-IR: no difference |
| 19 Rjabi et al. 2026 | systematic review | Ginger (Zingiber officinale) supplementation; vs. Control group (placebo or usual care) | Fasting blood sugar (FBS): improved (WMD = -12.79 mg/dL; 95% CI = -18.57); Insulin: improved (WMD = -1.33 µIU/ml; 95% CI = -1.94, -0.71); HOMA-IR: improved (WMD = -0.51; 95% CI = -0.68, -0.33) |
| 23 Al-Makhmari et al. 2025 | systematic review | Ginger (Zingiber officinale) alongside other herbs | regulation of carbohydrate metabolism enzymes: improved |
| 25 Paudel et al. 2025 | systematic review | Ginger supplements (form not specified); 1-3 g/day; for NVP 500-1,500 mg/day in divided doses; vs. Placebo/control (from meta-analyses) | glycosylated hemoglobin 1c: improved; fasting blood glucose: improved |
| 26 Victoria-Montesinos et al. 2025 | meta-analysis | Plant extracts from Zingiberaceae and Berberidaceae families; vs. Placebo or control (not further described) | Fasting blood glucose (FBS): improved (-1.06; 95% CI: -1.42 to -0.71); HbA1c: improved (-1.42; 95% CI: -2.64 to -0.19); Fasting insulin: improved (-0.75; 95% CI: -1.13 to -0.38) |
| 36 Schumacher et al. 2024 | meta-analysis | Capsules containing Zingiber officinale powder; 1.2 to 2 g/day, twice a day; 4 to 12 weeks; vs. Control (placebo) in included RCTs | Fasting blood glucose (FBS): no difference (no significant effect); HbA1c: no difference (no significant effect) |
Further studies in this area: 37 42 45 48 52 65 77 78 86 96 98 102 106 115 126 154 155 165 170
Ginger (Zingiber Officinale) and Chemotherapy-Induced Nausea: Human Studies
For nausea and vomiting during chemotherapy, the studies on ginger show a mixed picture. In a large randomized study in cancer patients, ginger capsules in addition to antiemetics reduced the severity of acute nausea compared with placebo, most strongly at the lower doses 56. A meta-analysis found that ginger capsules with antiemetics led to less frequent severe acute nausea and high-grade vomiting 22. A standardized ginger extract improved nausea-related quality of life and fatigue in the first cycle compared with placebo in a randomized study, but not in the second 95. These are offset by findings showing no difference: a systematic review with meta-analysis found no less frequent nausea and no less frequent vomiting with ginger 43. Only in a subgroup did acute vomiting occur less often 43. In cervical cancer under cisplatin and radiation, ginger capsules did not relieve nausea and vomiting compared with placebo 122. In a randomized study with four groups, ginger alone improved delayed symptoms, but not acute symptoms and delayed vomiting 64. In a randomized pilot study with applied oils, patients using peppermint oil had the least frequent nausea, followed by ginger oil and rapeseed oil; there was no difference in vomiting 116. Mainly ginger capsules and a standardized extract were tested. It remains open which dose works reliably for which chemotherapy.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 5 Burg et al. 2026 | systematic review · 2,409 participants | Ginger capsules, powder, tea, aromatherapy; vs. Heterogeneous studies, some with control groups | Chemotherapy-induced nausea and vomiting: unclear |
| 22 Lin et al. 2025 | meta-analysis | Ginger capsules or ginger-partitioned moxibustion; vs. Standard antiemetics or control | Incidence of grade 3 acute nausea: improved (RR, 0.19; P < .001); Incidence of high-grade overall vomiting: improved (RR, 0.47; P = .01); Incidence of mild vomiting (moxibustion): improved (RR, 0.56; P = .001) |
| 34 Noor et al. 2024 | review | 6-Gingerol (ginger constituent); vs. Control groups of included RCTs | Nausea-related quality of life: improved; Delayed nausea severity: improved |
| 41 Molassiotis et al. 2023 | systematic review | ingested ginger (Zingiber officinale); vs. other integrative and non-pharmacological therapies | recommendation for ingested ginger: unclear (conflicting evidence) |
| 43 Choi et al. 2022 | systematic review | Ginger supplementation as adjuvant treatment; not more than 1 g ginger per day (subgroup); above four days (subgroup); vs. placebo or antiemetic agents | incidence of acute nausea: no difference (p = 0.53); incidence of delayed nausea: no difference (p = 0.31); incidence of acute vomiting: no difference (p = 0.09) |
| 56 Ryan et al. 2012 | randomised controlled · 576 participants | Ginger capsules (250 mg) or placebo; 0.5 g, 1.0 g or 1.5 g ginger daily; 6 days, starting 3 days before chemotherapy; vs. Placebo, plus 5-HT3 antagonist on Day 1 | Severity of acute nausea on Day 1: improved (p = 0.003); Largest reduction in nausea intensity (0.5 g and 1.0 g): improved (p = 0.017 and p = 0.036) |
| 64 Chenbing et al. 2024 | randomised controlled · 172 participants | ginger (form/preparation not stated in abstract); vs. control, P6 acupressure, ginger plus acupressure | delayed chemotherapy-induced nausea and vomiting: improved (P < 0.05); functional living index-nausea: improved (P < 0.05); acute chemotherapy-induced nausea and vomiting: no difference (P>0.05) |
| 95 Marx et al. 2017 | randomised controlled · 51 participants | standardised ginger extract; 1.2 g per day; first three chemotherapy cycles; vs. placebo in addition to standard anti-emetic therapy | CIN-related quality of life (FLIE), Cycle 1: improved (p = 0.029); CINV-related quality of life, Cycle 1: improved (p = 0.043); global quality of life, Cycle 1: improved (p = 0.015) |
Further studies in this area: 116 122 125 160 169
Ginger (Zingiber Officinale) and Osteoarthritis: Human Studies
In osteoarthritis, two meta-analyses found less pain with ginger than with placebo 746. Inflammatory markers decreased in one of them and in a randomized study with ginger powder 4673. An extract from steamed ginger improved pain, WOMAC scores and patient assessment compared with placebo 75. In a network meta-analysis, ginger showed advantages in individual endpoints 3. A compress or patch with ginger relieved pain, fatigue and functional impairment in a study without a control group 118. Mainly ginger powder and extracts were tested; follow-up was mostly short, longer studies are still pending.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 3 Zhang et al. 2025 | meta-analysis · 4,599 participants | Ginger as a nutritional supplement, form/preparation not reported; vs. Placebo | WOMAC pain, stiffness, function and VAS pain: improved (ginger ... also demonstrated benefits in some outcomes) |
| 7 Del et al. 2017 | meta-analysis · 1,741 participants | Oral herbal medicines, including Zingiber officinale; vs. Placebo or control | pain improvement: improved |
| 46 Mathieu et al. 2022 | meta-analysis | Ginger supplementation (form not specified); vs. Placebo | Pain: improved (significantly decreased); Inflammatory markers: improved (significant decrease) |
| 73 Naderi et al. 2016 | randomised controlled · 120 participants | ginger powder capsules, 500 mg each; two capsules daily, 1 g/day; 3 months (12 weeks); vs. placebo capsules containing 500 mg starch | serum nitric oxide (NO): improved; hs-C-reactive protein (hs-CRP): improved |
| 75 Baek et al. 2024 | randomised controlled · 100 participants | GGE03, steamed ginger extract; 0.48 g/day GGE03 (1.6 g product); 12 weeks; vs. placebo (0 g/day GGE03) | pain (VAS): improved (statistically significantly decreased); K-WOMAC (total scores, sub-scores): improved (statistically significantly decreased); patient global assessment (PGA): improved (statistically significantly decreased) |
| 118 Therkleson et al. 2014 | case series · 20 participants | topical ginger compress (manual) or standardized ginger patch; 7 days treatment, optional 24 weeks self-treatment; vs. ginger compress versus ginger patch (no placebo group) | pain: improved (reduced by 48%); fatigue: improved (reduced by 49%); global effect: improved (reduced by 40%) |
| 129 Conrozier et al. 2019 | cohort study · 2,030 participants | capsules of glucosamine sulfate-copper sulfate-ginger root; two capsules once daily; 6 months; vs. no comparator arm, open-label observational study | adherence (good observance): improved (80%); pain decrease correlated with adherence: improved (P<0.0001) |
| 137 Żęgota et al. 2021 | study · 107 participants | Tregocel® (curcuminoids plus extracts of Harpagophytum, Boswellia, Apium, Zingiber); 36 weeks (mean observation 291.1 days); vs. no control group (single-arm, open-label) | 6-minute walk test: improved (26.0 (SD 30.4) m (p < 0.001)); VAS knee pain: improved (60.0 (IQR 50-72) mm ... to 21.0 (IQR 14-30) mm (p < 0.001)); regular knee OA medication use: improved (99.1% ... decreasing to 55.1%) |
Further studies in this area: 139 143 163 177
Ginger (Zingiber Officinale), Digestion and Gastrointestinal Complaints: Human Studies
In mild to moderate functional dyspepsia, a standardized extract from steamed ginger improved the GSRS total score and the subscores for abdominal pain, constipation, indigestion and reflux compared with placebo 79. In tuberculosis patients under treatment, gastrointestinal complaints decreased with ginger as with peppermint in a randomized study 61. A systematic review counts ginger-based preparations among the approaches that relieve complaints in functional dyspepsia 18. Another sees better digestive function consistently supported 48. In healthy young adults, standardized ginger root powder changed gut bacteria and relieved indigestion in a randomized study, but not other gastrointestinal complaints or gut function 94. The findings are based on ginger powder and extracts; studies on fresh rhizome, infusions and essential oil are still pending.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 18 Phang et al. 2026 | systematic review | Ginger-based supplements (preparation not reported); vs. Other dietary categories or controls | Symptom mitigation in functional dyspepsia: improved |
| 48 Anh et al. 2020 | systematic review | Ginger in various forms; vs. Control groups of included RCTs | digestive function: improved |
| 61 Latif et al. 2025 | randomised controlled · 200 participants | Ginger nutraceutical (dried, crushed); 1 g daily; 3 months intervention, 1 month washout; vs. Placebo, caraway 2 g, peppermint 3 mL daily | Relief of gastrointestinal disturbances: improved |
| 79 Baek et al. 2025 | randomised controlled · 80 participants | GGE03, steamed ginger extract; 480 mg per day; 12 weeks; vs. Placebo, double-blind, randomized, multicenter | GSRS total score: improved (p < 0.001); GSRS sub-scores (abdominal pain, constipation, indigestion, reflux): improved (p < 0.001 for all) |
| 94 Crichton et al. 2023 | randomised controlled · 51 participants | Standardized ginger root powder, 4 capsules per day; 1.2 g/d, totaling 84 mg/d active gingerols/shogaols; 14 d after a 1-wk run-in period; vs. Placebo (microcrystalline cellulose) | Relative abundance of phylum Actinobacteria: improved (U: 145.0; z: -2.1; P = 0.033); Abundance of several bacterial genera and families: improved (P < 0.05); Alpha and beta diversity: no difference |
| 141 Aregawi et al. 2025 | study · 47 participants | Ginger supplement (Zingiber officinale); 1080 mg/d in divided doses; 8 weeks; vs. no control group (open-label) | tolerability (good or excellent) (87.2%); bloating: unclear (14.9%); heartburn: unclear (12.8%) |
| 152 Pasta et al. 2026 | review | Ginger as nutraceutical, form not specified; vs. other dietary and nutraceutical options | Benefit in functional dyspepsia: improved |
| 157 Pastras et al. 2026 | review | Ginger extract (form not specified); vs. other plant extracts and placebo | IBS symptoms: unclear (mixed or inconsistent results) |
Further studies in this area: 161 162
Ginger (Zingiber Officinale) and Menstrual Pain: Human Studies
In menstrual pain, a meta-analysis found a reduction in pain intensity and pain duration with ginger compared with placebo 38. Compared with NSAIDs, there was no difference in pain intensity, nor compared with exercise 38. The evidence is considered low here because only this meta-analysis was evaluated and its individual studies carry a risk of bias 38.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 38 Moshfeghinia et al. 2024 | meta-analysis | Ginger (form not specified in abstract); vs. Placebo, NSAIDs, or exercise | Pain intensity vs. placebo: improved (SMD = -1.13; 95% CI = -1.59 to -0.68); Pain duration vs. placebo: improved (SMD = -0.29; 95% CI = -0.46 to -0.12); Pain intensity vs. NSAIDs: no difference (SMD = 0.01; 95% CI = -0.24 to 0.25) |
Ginger (Zingiber Officinale): Further Outcomes in Studies
Compared with placebo, ginger lowered inflammatory markers such as hs-CRP in type 2 diabetes 91, rheumatoid arthritis 90 and fatty liver 98. Extracts from steamed ginger lowered body fat in two randomized studies compared with placebo 7881, and in one also weight and body mass index 81. In healthy people, ginger powder did not change blood lipids, but in a laboratory test increased plasma's ability to take up cholesterol from cells 107. Antioxidative blood values improved compared with placebo with a standardized extract during chemotherapy 101 and with ginger powder in healthy people 107. In type 2 diabetes with periodontitis, ginger tablets in addition to gum treatment improved inflammatory values and gum pockets compared with placebo 99. In joint and muscle pain, a standardized extract from CO2 extraction and fermentation improved pain, stiffness and function compared with placebo 111. In muscle soreness after exertion, a ginger extract relieved pain in a controlled study 127. No difference from placebo was found for a ginger extract ointment for pain after episiotomy 85 and for ginger in performance and muscle soreness of cyclists 110. In allergic rhinitis, a ginger extract improved nasal complaints and quality of life similarly to the antiallergic loratadine, with less fatigue and drowsiness 80. In asthma, three measures of symptom control improved with ginger in addition to usual therapy, but not exhaled nitric oxide and blood eosinophils 109. The findings apply to the respective form tested — dried rhizome and powder, aqueous extract, standardized or alcoholic extract as well as essential oil — and cannot be transferred between the forms. The transferability to other baseline situations and the persistence beyond the short study durations remain open.
| Study | Design · participants | Preparation · dose · duration · comparison | Result |
|---|---|---|---|
| 1 Musazadeh et al. 2026 | systematic review · 43,570 participants | Ginger supplementation (form not specified); vs. Control in the included meta-analyses | C-reactive protein: improved (WMD: - 0.42 to - 1.00 mg/L); Interleukin-6: improved (WMD: - 0.45 to - 2.26 pg/mL); Malondialdehyde, glutathione peroxidase, total antioxidant capacity: improved |
| 4 Long et al. 2023 | meta-analysis · 3,852 participants | Ginger extract among 14 other polyphenol sources; vs. Control (placebo/standard care, not specified) | Disease activity score (DAS28): improved; Inflammation markers (CRP, ESR): improved; Oxidative stress: improved |
| 5 Burg et al. 2026 | systematic review · 2,409 participants | Ginger capsules, powder, tea, aromatherapy; vs. Heterogeneous studies, some with control groups | Xerostomia: unclear; Nutrition: unclear; Fatigue: unclear |
| 6 Wang et al. 2025 | meta-analysis · 2,062 participants | ginger as one of 15 plant substances; vs. standard treatment and other plant substances | quality of life: unclear; fatigue: unclear; pain: unclear |
| 8 Rafieipour et al. 2024 | meta-analysis · 1,309 participants | Ginger supplementation (form not specified in abstract); effective dose 2 g/d in dose-response analysis; effective duration longer than 8 weeks; vs. control groups of included RCTs | body weight: improved (WMD, -1.52 kg; 95%CI, -2.37, -0.66; P < 0.001); body mass index: improved (WMD, -0.58 kg/m2; 95%CI, -0.87, -0.30; P < 0.001); waist circumference: improved (WMD, -1.04 cm; 95%CI: -1.93, -0.15; P = 0.021) |
| 10 Kheiridoost-Langaroodi et al. 2022 | systematic review · 968 participants | five herbal medicines including ginger; vs. placebo or control, not reported | bone turnover markers BSAP, CTX, DPD, osteocalcin: no difference (p=0.50); femoral neck bone mineral density: improved (p=0.03); lumbar spine bone mineral density: no difference (p=0.28) |
| 11 Cho et al. 2026 | systematic review · 954 participants | Multi-herb formulations, including those containing Zingiber officinale Roscoe | directional shifts in selected genus-level gut microbiota taxa: unclear; mean accuracy of LOSO cross-validation: unclear (0.84) |
| 12 Atkins et al. 2026 | systematic review · 594 participants | Ginger alone or as adjunct to drugs/herbs; acute (2 hours) and preventive (3 months); vs. Placebo or active control (valproic acid, amitriptyline, sumatriptan) | Headache severity 2 hours post acute treatment (ginger + ketoprofen vs placebo + ketoprofen): improved (MD 1.27 lower, 95% CI 1.46 lower to 1.08 lower); Headache pain severity at 3 months (ginger added to active drug): improved (pooled MD -3.18, 95% CI -3.94 to -2.42); Pain relief/pain free at 2 hours (ginger + feverfew vs placebo or ginger vs sumatriptan): unclear |
Further studies in this area: 13 14 15 16 17 19 21 24 25 27 28 30 31 34 39 40 47 48 49 51 52 54 55 58 60 63 64 65 69 70 74 76 77 78 79 80 81 82 83 84 85 87 88 89 90 91 92 93 94 95 97 98 99 100 101 103 105 106 107 108 109 110 111 112 113 114 117 119 120 123 124 126 127 128 130 131 132 133 134 136 138 140 142 144 145 146 147 148 149 150 151 153 154 155 156 158 159 164 166 167 168 169 171 172 173 174 175 178
4. How Is Ginger (Zingiber Officinale) Dosed? Preparation, Dose and Duration in Studies
The studies examined dried rhizome and powder in capsules or tablets, fresh rhizome, aqueous infusions and mouth rinses, standardized and alcoholic extracts as well as essential oil as inhalation, aromatherapy or gel. For nausea in pregnancy, mainly capsules, powder and biscuits were examined, for osteoarthritis powder and extracts, for nausea after operations also essential oil. The exact doses and preparations are shown in the table.
| Preparation or form | Dose | Duration | Study |
|---|---|---|---|
| Ginger capsules (250 mg) or placebo | 0.5 g, 1.0 g or 1.5 g ginger daily | 6 days, starting 3 days before chemotherapy | 56 |
| Ayurvedic formulations SGCG and SGC (extracts of Tinospora cordifolia, Zingiber officinale, Emblica officinalis, Boswellia serrata) | — | 24 weeks | 57 |
| ginger essential oil aromatherapy | 20 minutes daily | 4 weeks | 58 |
| BV-4051, polyherbal Ayurvedic formulation (Ashwagandha, Boswellia, Ginger, Turmeric) | — | 14 days | 59 |
| 3 g ginger with three glasses of black tea | 3 g ginger daily | 8 weeks | 60 |
| Ginger nutraceutical (dried, crushed) | 1 g daily | 3 months intervention, 1 month washout | 61 |
| Aromatherapy: peppermint, ginger and lavender essential oils, each diluted to 1% | each 0.01 ml pure essential oil | — | 62 |
| 2% aqueous infusion of dried ginger rhizome (mouthwash) | 2% infusion, three times daily | twelve weeks | 63 |
| ginger capsules, 1000 mg | 1000 mg ginger | 12 weeks | 65 |
| Ginger (form and preparation not stated) | — | 4 days of intervention after 3 days without intervention | 66 |
| Capsules with five herbal extracts incl. ginger rhizome | two capsules orally every 8 hours | — | 67 |
| Ginger tablets (group G), 500 mg per tablet | 3 × 500 mg daily, 15 tablets total | 5 days | 69 |
| Swedish massage with aromatic ginger oil | 30 minutes, twice weekly | 5 weeks of treatment, follow-up to 15 weeks | 70 |
| highly purified plant-based nutraceutical with turmeric, dandelion, milk thistle, ginger | 60 mL twice daily | 180 days | 71 |
| Curcumax (ginger, turmeric, black pepper), capsule | one capsule daily | 8 weeks | 72 |
5. Is Ginger (Zingiber Officinale) Safe? Side Effects in Studies
In pregnant women, miscarriages, heartburn or drowsiness occurred no more frequently with ginger than with placebo or vitamin B6 920. A review found no harmful consequences for mother and child 53. Isolated cases of belching in pregnant women 25 and dizziness after moxibustion over ginger slices, a heat treatment of skin points, were reported 22. In a study with an Ayurvedic mixture of ginger, Tinospora cordifolia, Emblica officinalis and Boswellia serrata, the liver value SGPT rose without complaints in some participants 57.
| Study | Reported side effects |
|---|---|
| 3 Zhang et al. 2025 | No supplement associated with increased adverse events versus placebo |
| 4 Long et al. 2023 | Adding polyphenols did not increase adverse events |
| 5 Burg et al. 2026 | Two studies found disadvantages for chemotherapy-induced nausea and vomiting |
| 7 Del et al. 2017 | Adverse events assessed as secondary outcome |
| 9 Viljoen et al. 2014 | No significant risk of spontaneous abortion, heartburn or drowsiness |
| 20 Tahergorabi et al. 2026 | no increased risk of spontaneous abortion, heartburn, drowsiness |
| 22 Lin et al. 2025 | 2.8% dizziness after ginger-partitioned moxibustion |
| 23 Al-Makhmari et al. 2025 | Safety profiles noted as needing further research |
| 24 Piekarz et al. 2025 | Reduction of side effects of traditional therapies reported |
| 25 Paudel et al. 2025 | Belching in pregnant women |
| 30 Shu et al. 2025 | Reporting of adverse reactions deemed insufficient |
| 32 Gao et al. 2025 | well tolerated, minimal side effects, no harm to mother or fetus |
6. What Remains Open: Limits of the Evidence
- Some investigations examined ginger as part of mixtures; there the contribution of ginger alone remains open.
- Most studies were small and short; larger and longer studies are still pending.
- For nausea during chemotherapy the results contradict each other; above all the appropriate dose remains open.
- For fresh rhizome, aqueous infusions and essential oil there are clearly fewer controlled studies than for dried powder and extracts.
- For menstrual pain there is a meta-analysis whose individual studies carry a risk of bias 38.
7. Bottom Line: What Is Established About Ginger (Zingiber Officinale)
Ginger is the rhizome of Zingiber officinale and is examined in studies as fresh or dried rhizome, as powder, aqueous extract, standardized or alcoholic extract as well as essential oil. Best supported are less nausea in pregnancy, less pain in osteoarthritis and a lower fasting blood glucose in metabolic disorders. In functional dyspepsia, an extract of steamed ginger improved the complaints in a randomized study 79.
The findings apply in each case to the form and preparation studied and cannot be transferred between them. For nausea during chemotherapy the picture is mixed. Tolerability was predominantly good in the studies; larger and longer studies are still pending.
Frequently Asked Questions
How well has Ginger (Zingiber officinale) been studied in humans?
We evaluated 211 human studies on Ginger (Zingiber officinale), including 96 randomised controlled trials and 55 meta-analyses or systematic reviews; the controlled studies include 7,918 participants in total. As of 7 October 2026.
Does Ginger (Zingiber officinale) help with nausea and vomiting, including pregnancy? What the studies show
Does Ginger (Zingiber officinale) help with blood glucose and metabolism? What the studies show
Does Ginger (Zingiber officinale) help with chemotherapy-induced nausea? What the studies show
Does Ginger (Zingiber officinale) help with osteoarthritis? What the studies show
Does Ginger (Zingiber officinale) help with digestion and gastrointestinal complaints? What the studies show
Does Ginger (Zingiber officinale) help with menstrual pain? What the studies show
We evaluated one meta-analysis or systematic review. There are no controlled studies yet, only reviews; the strength of evidence is therefore low at most. Sources: 38
Which forms of ginger were examined in the studies?
Dried rhizome and powder, fresh rhizome, aqueous infusions and mouth rinses, standardized and alcoholic extracts as well as essential oil were examined. The findings apply in each case only to the form and preparation studied. The exact doses are shown in the table.
How well is ginger studied for nausea in pregnancy?
Meta-analyses and reviews found less nausea with ginger; for vomiting the effect is weaker and not established 92032. Mainly capsules, powder and biscuits were examined 32, in one review also fresh rhizome 50. Miscarriages, heartburn or drowsiness occurred no more frequently than with placebo or vitamin B6 920.
Does ginger help with osteoarthritis?
Two meta-analyses found less joint pain with ginger than with placebo 746, as did a randomized study with an extract of steamed ginger 75. The WOMAC value improved with the extract of steamed ginger 75; inflammatory markers fell in a meta-analysis and a study with ginger powder 4673. Most studies were small and short; larger and longer studies are still pending.
Does ginger work for nausea during chemotherapy?
The picture is mixed. In a large randomized study, ginger capsules in addition to antiemetics lowered the severity of acute nausea compared with placebo 56. A standardized extract improved nausea-related quality of life in the first cycle in another 95. A systematic review and a randomized study, by contrast, found no difference in nausea and vomiting 43122. In another, ginger alone improved the delayed complaints, not the acute ones 64.
Which side effects were reported?
In pregnant women, miscarriages, heartburn or drowsiness occurred no more frequently with ginger than with placebo or vitamin B6 920. A review found no harmful consequences for mother and child 53. In a study with an Ayurvedic mixture of ginger, Tinospora cordifolia, Emblica officinalis and Boswellia serrata, the liver value SGPT rose without complaints in some participants 57.
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Every statement on this page carries its evidence tier — proven, plausible or hypothesis — and leads to the original work. The decision in the individual case rests with the practitioner; we provide the connections.