Knowledge · Natural Compounds

Fenugreek (Trigonella Foenum-Graecum)

Fenugreek is a legume whose seeds have been shown in human studies to have mainly favorable effects on blood sugar and blood lipids.

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We evaluated 138 human studies on Fenugreek (Trigonella foenum-graecum), including 64 randomised controlled trials and 30 meta-analyses or systematic reviews; the controlled studies include 3,978 participants in total. As of 11 October 2026.

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1. What Is Fenugreek (Trigonella Foenum-Graecum)? Occurrence, Origin and Forms

Fenugreek is an annual legume in the Fabaceae family whose dried seeds are used as a spice and in the traditional medicine of the Mediterranean, Western Asia and South Asia. The seeds taste strong and slightly bitter and have long been part of cooking and home remedies there. Common modern forms are ground seeds, infusions and preserved seed extracts.

Fenugreek grows in warm, dry climates and is cultivated in southern Europe, North Africa, Western Asia and South Asia. It is examined almost exclusively through the seed and the preparations made from it.

Dried seeds are ground, steeped in hot water or extracted with water or alcohol, and part of the seed fibre is separated as galactomannan. Studies have examined whole and ground seeds, infusions, seed extracts and the fibre obtained from the seed.

Forms and Preparations Studied

  • Whole dried seeds
  • Ground seeds (seed flour)
  • Seed infusion or tea
  • Seed extract, aqueous or alcoholic
  • Fibre obtained from the seed (galactomannan)
  • Sprouted seeds

Not covered on this page:

  • Blue fenugreek (Trigonella caerulea), a different species
  • Guar gum and locust bean gum as other sources of galactomannan
  • Combination products with several herbs or other ingredients
  • Single isolated seed constituents supplied as a pure substance

2. What Does Fenugreek (Trigonella Foenum-Graecum) Do? Results by Area

AreaResult in controlled studiesStrength of evidenceStudiesParticipants
Blood Glucose and Sugar Metabolismmixedhigh15 meta-analyses · 21 controlled · 24 other1,245
Blood Lipidsmixedhigh9 meta-analyses · 11 controlled · 9 other803
Hormones and Testosteronemixedhigh3 meta-analyses · 10 controlled · 6 other830
Appetite and Satietymostly improvedmoderate0 meta-analyses · 5 controlled · 0 other98
Breastfeeding and Milk Productionmixedlow0 meta-analyses · 2 controlled · 5 other146
Other investigationsmixedhigh10 meta-analyses · 35 controlled · 18 other2,259

How to read the table: counted are human studies whose results concern the area. “High” means at least one meta-analysis and two controlled studies showing improvement, or at least three controlled studies of which three quarters show improvement, with at least 300 participants in total. “Moderate” means at least two controlled studies showing improvement, as a majority, or one meta-analysis alongside controlled studies. “Low” means one controlled study showing improvement. Where an area has no controlled study, the strength of evidence is at most “low” (result “reviews only” or “observational data only”). Everything else is “unclear”. A study counts as showing improvement when at least half of its outcomes in this area improved. Reviews of combination products do not count as meta-analyses; results that only describe side effects or shares of users do not count as an effect. The same study is counted only once.

3. What the Studies Show in Detail

Fenugreek (Trigonella Foenum-Graecum), Blood Glucose and Sugar Metabolism: Human Studies

Meta-analyses of controlled studies, predominantly in type 2 diabetes or prediabetes, found lower fasting blood glucose 31214151819 and lower HbA1c 2312141518 than with control. One of these meta-analyses found no significant difference in fasting blood glucose 2. In a randomized three-year study in prediabetes, fewer people developed type 2 diabetes with ground fenugreek than in the control group 85. Post-meal blood glucose was also lower than with control in several meta-analyses 31214152627. Against metformin, fenugreek in PCOS lowered blood glucose and insulin resistance less strongly, but improved blood lipids more strongly 81. Mainly ground seeds, seed extracts and individual standardized extracts such as Furocyst, Fenfuro and Fenuflakes were studied.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
2 Shabil et al. 2023meta-analysis · 894 participantsFenugreek (seeds, form not specified); vs. Control groupFasting blood glucose: no difference (MD: 3.70, 95% CI of -27.02, 19.62; p = 0.76); Postprandial blood glucose: no difference (MD: -10.61, 95% CI of -68.48, 47.26; p = 0.72); HbA1c: improved (MD: -0.88, 95% CI -1.49, -0.27; p = 0.00)
3 Kim et al. 2023meta-analysis · 706 participantsFenugreek (form not specified); vs. Control groupFasting blood glucose: improved (significantly reduced); 2-h plasma glucose during OGTT: improved (significantly reduced); HbA1c: improved (significantly reduced)
9 Juhász et al. 2026systematic reviewfenugreek (12 seed powder, 7 seed extract, 1 leaf extract) plus guar, locust bean and tara gum; not reported; not reported; vs. guar gum, locust bean gum, tara gumglycemic outcomes: improved
10 Amiri et al. 2026systematic reviewFenugreek (Trigonella foenum-graecum), form unspecifiedHypoglycemia
11 Al-Makhmari et al. 2025systematic reviewFenugreek (Trigonella foenum-graecum), form unspecified; vs. other herbs or controls in the included studiesglycaemic control: improved
12 Chehregosha et al. 2025meta-analysisFenugreek seed (Trigonella foenum-graecum); vs. Control groupFasting blood glucose: improved (WMD: - 16.75 mg/dl; 95 % CI: - 23.36, - 10.15; p<0.001); 2-hr postprandial glucose: improved (WMD: - 22.28 mg/dl; 95 % CI: - 34.42 to - 10.15; p<0.001); HbA1c: improved (WMD: - 0.63 mg/dl; 95 % CI: - 0.76 to - 0.51; p<0.001)
13 de et al. 2024systematic reviewFlour-based foods, including fenugreek powder; 1.5 g to 36 g/day; six weeks to 120 days; vs. Control groups of included RCTsparameters of glucose homeostasis: improved (significant results)
14 Shakil et al. 2024meta-analysisFenugreek seed, powder form; 2-5 mg; vs. ControlFasting blood sugar: improved (P<0.001); HbA1c: improved (P<0.001); Postprandial glucose: improved (P<0.001)

Further studies in this area: 17 18 19 20 21 22 23 25 26 27 29 30 31 32 34 49 55 59 61 62 63 69 71 72 74 75 76 78 80 81 82 85 88 93 94 95 96 100 104 106 107 109 110 111 112 114 117 118 121 123 124 126

Fenugreek (Trigonella Foenum-Graecum) and Blood Lipids: Human Studies

Several meta-analyses found lower triglycerides 34719 and higher HDL cholesterol 3471819 than with control, as did one randomized study for triglycerides 62 and one for HDL cholesterol 61. Total and LDL cholesterol fell in two meta-analyses 47; others found no significant difference in LDL cholesterol 326 or in triglycerides 1826. Predominantly seed extracts were studied, along with ground seeds and, in individual works, unspecified seed forms. The strength of evidence is high, but many studies are small and short, and the seed form along with amount and standardized fraction remains unclear in several works.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
3 Kim et al. 2023meta-analysis · 706 participantsFenugreek (form not specified); vs. Control groupTotal cholesterol: improved (significantly improved); Triglycerides: improved (significantly improved); HDL-C: improved (significantly improved)
4 Askarpour et al. 2020meta-analysis · 560 participantsFenugreek supplementation (form not specified); vs. Control/placebo (not specified)Total cholesterol: improved (WMD = -9.371 mg/dL; 95% CI: -15.419, -3.323, p = 0.002); Triglycerides: improved (WMD = -13.776 mg/dL; 95% CI: -26.636, -0.916, p = 0.036); LDL cholesterol: improved (WMD = -6.590 mg/Dl; 95% CI: -13.042, -0.137, p = 0.045)
7 Heshmat-Ghahdarijani et al. 2020meta-analysis · 281 participantsFenugreek supplementation (form not specified); vs. Control group or pre-postTotal cholesterol: improved (-1.13 [-1.88, -0.37]; p = .003); LDL cholesterol: improved (-1.26 [-2.09, -0.43]; p = .003); Triglycerides: improved (-1.07 [-1.82, -0.33]; p = 0.005)
9 Juhász et al. 2026systematic reviewfenugreek (12 seed powder, 7 seed extract, 1 leaf extract) plus guar, locust bean and tara gum; not reported; not reported; vs. guar gum, locust bean gum, tara gumlipid parameters: unclear
11 Al-Makhmari et al. 2025systematic reviewFenugreek (Trigonella foenum-graecum), form unspecified; vs. other herbs or controls in the included studieslipid profile: improved
17 Sarker et al. 2024reviewFenugreek seeds and isolated seed compoundslipid profiles: improved
18 Vajdi et al. 2024meta-analysisFenugreek supplementation (form unspecified); vs. Control group (clinical trials)Total cholesterol (TC): improved (WMD: 33.10 mg/dL; 95 % CI: 64.31 to -1.88); LDL-C: improved (WMD: 29.14 mg/dL; 95 % CI: 55.45 to -2.83); HDL-C: improved (WMD: 5.68 mg/dL; 95 % CI: 3.51 to 7.85)
19 Fakhr et al. 2023meta-analysisFenugreek preparations (form not specified in abstract); not reported; not reported; vs. Control groups of included RCTsTriglycerides: improved (-20.12 mg/dL; 95 % CI: -34.238, -5.994; P < 0.001); HDL cholesterol: improved (WMD: 3.55 mg/dL; 95 % CI: 1.98, 5.12; P < 0.001)

Further studies in this area: 25 26 31 32 41 51 61 62 64 71 76 81 85 89 95 96 97 99 106 109 118

Fenugreek (Trigonella Foenum-Graecum), Hormones and Testosterone: Human Studies

In men, meta-analyses found a small increase in total testosterone 524; a more recent review rates the evidence as very uncertain and saw no stable effect on free testosterone 8. Under strength training, testosterone rose in two placebo-controlled studies with extracts 5768, while in older men with prostate complaints it remained unchanged 38. In women during and after menopause, estradiol rose compared with placebo in two controlled studies 4165, but not in a third 36. In younger women with low sexual desire, estradiol and free testosterone rose 43. Mixed preparations of fenugreek with shatavari 35, with Lespedeza cuneata 84, with minerals such as Testofen 58 or with added nutrients 40 show only what the respective mixture does. The findings come predominantly from seed extracts, partly standardized, partly hydroalcoholic; for ground seeds, infusion or germinated seeds, no controlled results are available in this area. The populations and endpoints are very different, and several studies were small or of short duration.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
5 Isenmann et al. 2023meta-analysis · 449 participantsFenugreek extracts; chronic application; vs. control grouptotal testosterone: improved (SMD: 0.32; 95% CI: 0.09 0.55); free testosterone: no difference (SMD: 0.24; 95% CI: -0.04, 0.52)
8 Yang et al. 2026meta-analysisOral fenugreek-derived preparations (form not specified); vs. PlaceboTotal testosterone (SMD): improved (SMD: 0.25, 95% CI: 0.02, 0.48; p = 0.037); Free testosterone (SMD): no difference (SMD: 0.08, 95% CI: -0.48, 0.63; p = 0.725)
24 Mansoori et al. 2020meta-analysisFenugreek extract (glycoside extract); vs. Control groupTotal serum testosterone: improved
31 Singh et al. 2023randomised controlled · 208 participantsFurocyst®, patented standardized Trigonella foenum-graecum extract; 2 capsules of 500 mg/day; not reported; vs. placebo (95) vs. Furocyst® (113), double-blind randomizedLH and FSH: improved; TSH: improved; prolactin and SHBG: improved
36 Steels et al. 2017randomised controlled · 115 participantsStandardized de-husked Trigonella foenum-graecum seed extract; 600 mg per day; 12 weeks; vs. Placebo, double-blind randomizedSerum estradiol levels: no difference
38 Rao et al. 2020randomised controlled · 100 participantsstandardised Trigonella foenum-graecum (fenugreek) extract; 600 mg per day orally; 12 weeks; vs. placebo, double-blind randomisedtestosterone, free testosterone, SHBG: no difference (remained unchanged)
41 Shamshad et al. 2016randomised controlled · 88 participantsstandardized fenugreek extract (FenuSMART™); 1000 mg/day; 90 days; vs. placebo, double-blind randomizedplasma estradiol: improved (increase in plasma estradiol (120%))
43 Rao et al. 2015randomised controlled · 80 participantsstandardised Trigonella foenum-graecum seed extract (Libifem); 600 mg/day; two menstrual cycles (8 weeks); vs. placebo, double-blind, randomisedfree testosterone: improved (significant increase); estradiol (E2): improved (significant increase)

Further studies in this area: 47 57 65 68 74 95 96 97 98 104 108

Fenugreek (Trigonella Foenum-Graecum), Appetite and Satiety: Human Studies

In two placebo-controlled studies with healthy men, a seed extract reduced spontaneous fat consumption, in one of them only at the higher dose 6977. Isolated fenugreek fiber at breakfast increased satiety, but energy intake at the lunch buffet did not differ significantly from control 75. Total energy intake also did not differ significantly with seed extract 77. In a small crossover study with nine women, fenugreek tea reduced hunger and increased satiety compared with placebo tea, without changing food intake at the lunch buffet 79. The findings come from small, short investigations with seed extract, isolated fiber and tea, and the strength of evidence is moderate.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
69 Chevassus et al. 2010randomised controlled · 39 participantshydro-alcoholic fenugreek seed extract; fixed dose (amount not stated); 6 weeks; vs. placebo, double-blind, randomizedfat reported energy intake/total energy expenditure ratio: improved (0.26 +/- 0.02 vs. 0.30 +/- 0.01; P = 0.032)
74 Bhalerao et al. 2026randomised controlled · 20 participantsseed powder of T. foenum-graecum, T. balansae or combination; 2–3 g/day; 14 days; vs. three groups: FS1, FS2, FS3subjective appetite improvement: unclear (4 participants in each group)
75 Mathern et al. 2009randomised controlled · 18 participantsisolated fenugreek fiber in test breakfast; 0 g, 4 g or 8 g; 3.5 h postprandial; vs. 0 g (control) vs. 4 g vs. 8 gsatiety and fullness ratings (VAS): improved (P < 0.05); hunger and prospective food consumption (VAS): improved (P < 0.05); energy intake at ad libitum lunch buffet: no difference (p = 0.11)
77 Chevassus et al. 2009randomised controlled · 12 participantsfenugreek seed extract; 588 and 1176 mg; three 14-day periods, 14-day washout; vs. placebo, double-blind, randomized, cross-overDaily fat consumption: improved (3.73 vs. 4.51 MJ day(-1), -17.3% vs. placebo, 95% CI -1.51 to -0.05, n = 12, P = 0.038); Total energy intake: no difference (9.97 vs. 11.29 MJ day(-1), -11.7% vs. placebo, 95% CI -2.91 to 0.26, n = 12, P = 0.094)
79 Bae et al. 2015randomised controlled · 9 participantsFenugreek tea (FGT) compared with fennel tea and placebo tea; vs. Placebo tea, 3-way crossover, single-blindedSubjective hunger (VAS): improved (p < 0.05); Prospective food consumption (VAS): improved (p < 0.05); Feelings of fullness (VAS): improved (p < 0.05)

Fenugreek (Trigonella Foenum-Graecum), Breastfeeding and Milk Production: Human Studies

Among mothers of preterm infants, milk volume was higher with fenugreek capsules than with placebo on the seventh day, but no longer significant on the fifteenth day; prolactin and the weight of the newborns did not differ 47. An herbal nursing tea with fenugreek increased milk volume on the third day after birth compared with placebo 48. In a randomized study, mothers drank black tea with or without fenugreek seed 45. With fenugreek, infant weight, head circumference, wet diapers and stools increased compared with baseline, but not in the comparison group 45. Given alone, fenugreek did not improve breastfeeding success in a randomized study; only together with honey did it increase 46. The evidence is weak; the studies tested different preparations such as capsules, tea and drops and sometimes mixtures, so the findings cannot readily be transferred to the seed alone.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
45 Ghasemi et al. 2015randomised controlled · 78 participantsHerbal tea with 7.5 g fenugreek seed powder plus 3 g black tea powder; 7.5 g fenugreek seed powder, three times a day; four weeks; vs. Herbal tea with 3 g black tea powder, three times a dayinfant weight gain: unclear (5282.0513 ± 1021.51121 to 6383.0769 ± 952.06190); head circumference: unclear (38.3103 ± 1.62736 to 39.9256 ± 1.50660); number of wet diapers per day: unclear (5.2821 ± 0.93044 to 8.1648 ± 1.20620)
47 Rouhi et al. 2025randomised controlled · 68 participantsFenugreek capsules (500 mg) vs. placebo; 500 mg three times daily; from day 5 to day 14 after delivery; vs. Placebo capsulesBreast milk volume on day 7: improved (p =0.017); Breast milk volume on day 15: no difference (p =0.073)
105 Damanik et al. 2006studyFenugreek seeds (comparison group); 28 days; vs. Coleus amboinicus and Molocco+B12 tabletsmilk volume: improved (20%)
118 Nagulapalli et al. 2017reviewFenugreek (seeds, extract)galactogogue effect: improved
119 Dietz et al. 2016reviewTrigonella foenum-graecum (fenugreek) as galactagogueEfficacy as galactagogue: unclear
122 Zapantis et al. 2012reviewFenugreek as a galactagogue herbMilk supply: improved
125 2006reviewFenugreek seeds, also in multi-ingredient mixtures; 1 to 6 g daily; about 25 g or more daily may lower cholesterol and blood sugar; vs. Placebo or no treatment; some multi-ingredient combinationsMilk supply: improved (43% thought it increased milk supply); Milk supply: worsened (5% thought it decreased their milk supply); Galactogogue effect: improved (mild galactogogue effect)

Fenugreek (Trigonella Foenum-Graecum): Further Outcomes in Studies

In three placebo-controlled studies, extracts from seeds or seed husk alleviated menopausal symptoms such as hot flashes 364165. In first-time mothers after birth, a seed extract improved self-reported sleep quality compared with placebo 50. In menstrual pain, seed powder alleviated pain intensity more than placebo 86; against the painkiller mefenamic acid, it acted similarly 56. With seed extract, muscle strength rose more than with placebo in several controlled studies 60646883; with training, body fat percentage also fell 576483. One meta-analysis found lower systolic blood pressure 19, a placebo-controlled study in type 2 diabetes only lower diastolic 49. Two further studies showed reductions only compared with baseline 4263. A nursing tea of fenugreek, bitter fennel, anise, coriander and other herbs showed no difference compared with placebo in quality of life and breastfeeding self-efficacy 54. A fiber mixture of fenugreek, guar gum and wheat bran lowered BMI and waist circumference only compared with baseline 37. The strength of evidence is high, but many studies are small and short, and the forms studied and standardized fractions are often not precisely stated.

StudyDesign · participantsPreparation · dose · duration · comparisonResult
1 Mohit et al. 2026meta-analysis · 1,171 participantsFenugreek supplements (form not specified in abstract); Subgroup >1 g/day; vs. Control groupAlkaline phosphatase (ALP): no difference (SMD = -0.21, 95% CI = -0.44, 0.03); Aspartate aminotransferase (AST): no difference (WMD = 0.03 IU/L, 95% CI = -0.12 to 0.18); Alanine aminotransferase (ALT): no difference (WMD = -1.41 IU/L, 95% CI = -3.07, 0.26)
3 Kim et al. 2023meta-analysis · 706 participantsFenugreek (form not specified); vs. Control groupBody mass index: no difference (no significant differences)
4 Askarpour et al. 2020meta-analysis · 560 participantsFenugreek supplementation (form not specified); vs. Control/placebo (not specified)Body weight: no difference (WMD = 0.223 kg; 95% CI: -0.509, 0.955, p = 0.551); Body mass index: no difference (WMD = 0.091 kg/m2; 95% CI: -0.244, 0.426, p = 0.596)
5 Isenmann et al. 2023meta-analysis · 449 participantsFenugreek extracts; chronic application; vs. control grouplean body mass: no difference (SMD: 0.19; 95% CI: -0.10, 0.49); fat mass: no difference (SMD: -0.19; 95% CI: -0.44, 0.05); leg press performance: no difference (SMD: 0.22; 95% CI: -0.02, 0.47)
6 Amini et al. 2023meta-analysis · 373 participantsFenugreek seed supplementation; Subgroup analysis: ≥ 15 g/day; Subgroup analysis: ≤ 12 weeks; vs. Control group (placebo/no supplementation)Systolic blood pressure: improved (WMD: 3.46 mmHg, 95% CI - 6.33, - 0.59, P=0.018); Diastolic blood pressure: no difference (WMD: 3.19 mmHg; 95% CI, - 5.82 to 12.21, P=0.488)
9 Juhász et al. 2026systematic reviewfenugreek (12 seed powder, 7 seed extract, 1 leaf extract) plus guar, locust bean and tara gum; not reported; not reported; vs. guar gum, locust bean gum, tara gumbody weight and body mass index: unclear
10 Amiri et al. 2026systematic reviewFenugreek (Trigonella foenum-graecum), form unspecifiedMost common adverse effect; Allergic reactions; Maple syrup odor in urine, sweat, or skin
13 de et al. 2024systematic reviewFlour-based foods, including fenugreek powder; 1.5 g to 36 g/day; six weeks to 120 days; vs. Control groups of included RCTsblood pressure measurements: improved (improvements)

Further studies in this area: 16 18 19 25 28 31 32 34 36 38 41 42 43 44 47 49 50 52 53 56 57 59 60 61 62 63 64 65 66 67 68 69 70 73 81 83 86 87 90 91 92 95 96 97 98 101 102 103 110 113 115 116 118 120 125

4. How Is Fenugreek (Trigonella Foenum-Graecum) Dosed? Preparation, Dose and Duration in Studies

The studies predominantly used seed extracts, some standardized to furostanol saponins such as Furocyst, Fenfuro or Fenuflakes, as well as ground seeds, infusions and, in individual papers, isolated galactomannan fiber. For whole and germinated seeds, hardly any controlled results are available in the areas evaluated. The doses and treatment durations are shown in the table.

Preparation or formDoseDurationStudy
Furocyst®, patented standardized Trigonella foenum-graecum extract2 capsules of 500 mg/daynot reported31
Furocyst, fenugreek seed extract rich in furostanolic saponinsFurocyst twice daily (BD)12 weeks (three months)32
lactation cookies with galactagogues (fenugreek, oatmeal, brewer's yeast, flax seeds)56.5 g cookies daily1 month33
Fenfuro, fenugreek seed extract enriched in furostanolic saponins500 mg twice daily90 days34
Fenavari, standardized extract of Trigonella foenum-graecum and Asparagus racemosus300 mg or 500 mg once daily84 days35
Standardized de-husked Trigonella foenum-graecum seed extract600 mg per day12 weeks36
Fibernat, fiber mixture of fenugreek, guar gum and wheat bran10 g twice daily6 months37
standardised Trigonella foenum-graecum (fenugreek) extract600 mg per day orally12 weeks38
Agent containing fenugreek, olive leaf polyphenols and bergamot extract—6 months39
TrigozimR fenugreek extract with essential nutrients0, 600, 1200, 1800 mg/day, 3 tablets12 weeks40
standardized fenugreek extract (FenuSMART™)1000 mg/day90 days41
fenugreek seed extract5 cc4 months42
standardised Trigonella foenum-graecum seed extract (Libifem)600 mg/daytwo menstrual cycles (8 weeks)43
Aqueous extract of fenugreek seeds as syrup—4 weeks44
Herbal tea with 7.5 g fenugreek seed powder plus 3 g black tea powder7.5 g fenugreek seed powder, three times a dayfour weeks45

5. Is Fenugreek (Trigonella Foenum-Graecum) Safe? Side Effects in Studies

The controlled studies with fenugreek alone report good tolerability without serious side effects 33134384147515657. Mild gastrointestinal complaints are mentioned most frequently 31026. Possible hypoglycemia, hypokalemia, allergic reactions and drug interactions are mentioned occasionally 10; details are shown in the table.

StudyReported side effects
1 Mohit et al. 2026Safety should be further investigated
3 Kim et al. 2023Mild gastrointestinal side effects; no severe adverse events, no hepatic or renal toxicity
8 Yang et al. 2026Safety summarized descriptively, no numbers reported
9 Juhász et al. 2026not reported
10 Amiri et al. 2026Mild gastrointestinal discomfort most common; hypoglycemia, potential hypokalemia, allergic reactions, maple syrup odor, drug interactions
11 Al-Makhmari et al. 2025Safety profiles noted as needing consideration, no data given
16 Hassanzadeh et al. 2024Side effects reported but not quantified
19 Fakhr et al. 2023not reported
23 Willcox et al. 2021no serious adverse effects reported
26 Gong et al. 2016No liver or kidney toxicity; mainly gastrointestinal discomfort
28 Posadzki et al. 2013Only minor adverse effects reported
31 Singh et al. 2023no significant adverse events observed

6. What Remains Open: Limits of the Evidence

  • Many studies are small and of short duration, which limits the informative value despite high certainty of evidence in individual areas.
  • The seed form together with the amount and standardized proportion remains unclear in several papers, so that findings cannot always be assigned to a preparation.
  • For ground seeds, infusion and germinated seeds, no controlled results are available in several areas.
  • True combination products such as breastfeeding teas with fennel and anise or a fiber mixture with guar gum and wheat bran do not allow any conclusion about the seed alone 3754.
  • The populations and endpoints studied are very different, which makes comparison between the studies difficult.

7. Bottom Line: What Is Established About Fenugreek (Trigonella Foenum-Graecum)

Fenugreek seed extracts and ground seeds showed favorable effects on blood sugar and blood lipids in several controlled studies and meta-analyses; for testosterone in men, the increases are small and still uncertain. Placebo-controlled studies also found initially more breast milk, fewer menopausal symptoms and menstrual pain, as well as less body fat and more muscle strength with training. The certainty of evidence is high in several areas, but many studies are small and short, and the seed form studied together with the amount and standardized proportion often remains unclear. Next to be clarified are larger, longer studies with precisely described preparation; findings on combination products apply only to the respective mixture.

Frequently Asked Questions

How well has Fenugreek (Trigonella foenum-graecum) been studied in humans?

We evaluated 138 human studies on Fenugreek (Trigonella foenum-graecum), including 64 randomised controlled trials and 30 meta-analyses or systematic reviews; the controlled studies include 3,978 participants in total. As of 11 October 2026.

Does Fenugreek (Trigonella foenum-graecum) help with blood Glucose and Sugar Metabolism? What the studies show

We evaluated 15 meta-analyses or systematic reviews, 21 controlled studies and 24 further studies; the controlled studies include 1,245 participants in total. Result of the controlled studies: mixed. Strength of evidence under our published rules: high. Sources: 23910

Does Fenugreek (Trigonella foenum-graecum) help with blood Lipids? What the studies show

We evaluated 9 meta-analyses or systematic reviews, 11 controlled studies and 9 further studies; the controlled studies include 803 participants in total. Result of the controlled studies: mixed. Strength of evidence under our published rules: high. Sources: 3479

Does Fenugreek (Trigonella foenum-graecum) help with hormones and Testosterone? What the studies show

We evaluated 3 meta-analyses or systematic reviews, 10 controlled studies and 6 further studies; the controlled studies include 830 participants in total. Result of the controlled studies: mixed. Strength of evidence under our published rules: high. Sources: 582431

Does Fenugreek (Trigonella foenum-graecum) help with appetite and Satiety? What the studies show

We evaluated 5 controlled studies; the controlled studies include 98 participants in total. Result of the controlled studies: mostly improved. Strength of evidence under our published rules: moderate. Sources: 69747577

Does Fenugreek (Trigonella foenum-graecum) help with breastfeeding and Milk Production? What the studies show

We evaluated 2 controlled studies and 5 further studies; the controlled studies include 146 participants in total. Result of the controlled studies: mixed. Strength of evidence under our published rules: low. Sources: 4547105118

Which forms of fenugreek were studied?

Seed extracts were tested most frequently, some standardized to furostanol saponins such as Furocyst, Fenfuro or Fenuflakes. In addition, ground seeds, infusions and, in individual papers, isolated galactomannan fiber were used. For whole and germinated seeds, hardly any controlled results are available in the areas evaluated.

How well is fenugreek tolerated?

The controlled studies with fenugreek alone report good tolerability without serious side effects 33134384147515657. Mild gastrointestinal complaints are mentioned most frequently 31026. Possible hypoglycemia, hypokalemia, allergic reactions and drug interactions are mentioned occasionally 10.

Do human studies show an effect on blood sugar?

Yes, meta-analyses of controlled studies, predominantly in type 2 diabetes or prediabetes, found lower levels of fasting blood sugar, HbA1c and post-meal blood sugar than with control 3121415. The robustness is high, but many studies are small and short.

What do the studies on blood lipids show?

Two meta-analyses found lower total cholesterol, LDL and triglyceride levels as well as higher HDL cholesterol than with control 47. One meta-analysis in diabetes confirmed only total cholesterol 26.

Do the results also apply to combination products with other ingredients?

No, findings on combination products concern the mixture, not the seed alone. This applies, for example, to a breastfeeding tea with fennel, anise and coriander 54, a fiber mixture with guar gum and wheat bran 37 and an extract with added nutrients 40.

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International Health Research · https://ih-research.com/en/knowledge/fenugreek/ · Last updated: 2026-10-15