News · 04 Aug 2026

Systematic Review: Sulforaphane Modulates Epigenetic Mechanisms and PRMT5 Inhibition

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A systematic review of 118 studies synthesizes evidence on how sulforaphane from cruciferous vegetables affects epigenetic processes and the PRMT5-MEP50 complex.

What the Research Says

The review analyzed 118 studies, including clinical and preclinical research. Sulforaphane elevates NAD+ levels, activates sirtuins, and inhibits PRMT5, which may slow tumor growth. Clinical applicability remains to be confirmed.

Source

Frontiers in pharmacology: Dietary sulforaphane in cancer chemoprevention: epigenetic regulation and PRMT5-MEP50 complex inhibition-a systematic review. (2026-08-04)

Full evidence overview: Sulforaphane

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International Health Research · https://ih-research.com/en/news/2026-09-sulforaphan/ · Last updated: 2026-09-20