Systematic Review with Meta-Analysis: Early-Life Omega-3 and Asthma Risk
A systematic review with meta-analysis of randomized controlled trials examined early-life omega-3 fatty acids for preventing childhood asthma and wheezing. Supplementation reduced risk in a dose-dependent manner, and dose-response analysis confirmed a linear relationship. The authors report substantial protection for high-dose regimens, particularly those involving EPA.
What the Research Says
The analysis followed PRISMA guidelines; three reviewers independently evaluated the studies and extracted data. Subgroup analyses revealed no heterogeneity with respect to study location, allergy risk or follow-up duration.
Source
Full evidence overview: Omega-3
Every statement on this page carries its evidence tier — proven, plausible or hypothesis — and leads to the original work. The decision in the individual case rests with the practitioner; we provide the connections.