Knowledge · Therapies

Microneedling Explained Simply

Microneedling is a procedure in which fine needles open the skin. This page explains in simple words what happens during this and what studies have shown so far.

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1. What It Is About

Microneedling is not an active substance but a procedure. A device with fine needles creates many small, controlled injuries in the skin and thereby opens its uppermost protective layer. How deeply the needles reach depends on their length. A common variant combines the needles with radiofrequency energy that delivers heat into deeper skin layers. After piercing, a preparation is usually applied, such as a serum or a solution. It is precisely this combination that shapes the research: the procedure is predominantly tested as an access route and enhancer, less often as a stand-alone treatment. There is no dose in the usual sense. Instead, needle length, application pressure, number of passes, interval between sessions and the device are decisive — and these details differ from study to study. Therefore, findings from one investigation cannot be transferred directly to another.

2. What Studies Show

The best-studied indication is hair loss in men. In a study with 100 patients, one group received additional treatment with fine needles in addition to minoxidil, while the other received only minoxidil. After twelve weeks, hair count had risen markedly more in the needling group than in the comparison group 1. The work was designed as a pilot study, that is, an initial exploration, and the observation period was short.

In melasma, a patchy brown discolouration of the skin, a study with 60 patients compared two approaches: injections of tranexamic acid alone and the same injections combined with microneedling. In the microneedling group the skin condition improved more, and more patients achieved a marked improvement 2. No serious adverse effects occurred in either group.

Another study in 19 men treated two halves of the scalp differently: on one side radiofrequency microneedling and minoxidil were used together, on the other side only minoxidil. After five months both the number and the thickness of hairs had increased more on the combination side 5.

In acne, a study in 20 persons examined fractional microneedling with radiofrequency. After twelve weeks the inflammatory lesions on the treated side had decreased markedly, as had the non-inflammatory lesions 4.

For acne scars, a review summarises nine randomised controlled trials and classifies microneedling as effective, both alone and in combination 10. In a direct comparison with a laser both sides improved similarly, yet microneedling was better tolerated, with shorter recovery time and fewer adverse effects 7.

3. What Remains Unclear

Almost all robust studies test microneedling together with a second intervention, for example minoxidil, tranexamic acid or platelet-rich plasma. How much the needling itself contributes cannot be deduced from these data. Anyone wishing to classify the procedure as a stand-alone measure requires comparison groups without a second intervention. The precise mechanism of action is also considered not yet determined. Many controlled studies carry notes such as pilot study or open comparison, which limits their weight. A large proportion of the work moreover measures safety and tolerability rather than efficacy. Larger investigations with long-term follow-up and uniform device settings are still outstanding; several reviews call specifically for these steps 10 9. In melasma the question remains open whether microneedling is superior to applied hydroquinone 8.

4. What This Means in Everyday Life

Microneedling is a procedure that opens the skin in a controlled manner. In the studies it was mostly tested together with a second treatment, and in this combination improvements were observed in hair loss, acne scars, melasma and acne. As a stand-alone measure it has been investigated far less often. The tolerability profile is noteworthy: in several comparisons with laser or radiofrequency procedures microneedling performed similarly well and was better tolerated, with shorter recovery time. Transient redness and temporary darkening of the skin after treatment are reported frequently; lasting complaints are rare 3. Anyone interested in the procedure will find no uniform protocol in the studies — needle length, interval and number of sessions differ. What needs to be clarified next is whether and how strongly needling also works without a second treatment.

All details with study numbers and sources: detailed page on microneedling. For children: Microneedling for children.

Frequently Asked Questions

Does Microneedling Hurt?

In the studies, pain was rated differently. In a comparison with a laser, the needle treatments were described as better tolerated, and the recovery time was shorter 6. How much it hurts also depends on how deep the needles reach.

How Many Sessions Are Usual?

There is no uniform procedure. Some studies treated weekly, others at monthly intervals over several sessions. Several reviews criticise exactly this inconsistency and call for fixed treatment protocols 10.

Does Microneedling Help Against Hair Loss?

In a study with 100 patients, the hair count increased more with additional microneedling than with minoxidil alone 1. Another study on 19 men found the same for the combination with radiofrequency 5. The observation periods were short, so long-term effects have not yet been clarified.

Sources

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    Hou A, Cohen B, Haimovic A, Elbuluk N · 2017
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    Neagu N, Conforti C, Agozzino M, Marangi GF, Morariu SH, Pellacani G et al. · 2022
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Every statement on this page carries its evidence tier — proven, plausible or hypothesis — and leads to the original work. The decision in the individual case rests with the practitioner; we provide the connections.

International Health Research · https://ih-research.com/en/knowledge/microneedling/plain/ · Last updated: 2026-10-15